摘要
摘要目的探讨单唾液酸四已糖神经节苷酯注射液治疗急性脑梗死的有效性和安全性.方法选择发病４８小时内的急性脑梗死患者２８６例,随机分为单唾液酸四已糖神经节苷酯注射液治疗组(１４３例)及安慰剂对照组(１４３例).结果治疗组疗效优于对照组,差异有极显著性(P＜０．００１);２组均无药物严重不良事件发生.结论单唾液酸四已糖神经节苷酯注射液治疗急性脑梗死是安全有效的.关键词单唾液酸四已糖神经节苷酯急性脑梗死有效性安全性DoubleＧblindplaceboＧcontrolled,randomizedClinicalStudyofmonosialotetrahexosylganglioside(GM１)inthetreatmentofAcuteIschemicStrokePatientsFanTaiＧgen１,WangGuoＧtuan２LiuJianＧhong２(１DepartmentofNeurology２DepartmentofpharmacyKaramayCentralHospitalKaramay８３４０００XinJiang)AbstractObjectiveToinvestigatetheeffectivenessandsafetyoffoursingleＧandＧsalivaryacidintreatingacutecerebralinfarction．Methods２８６patientswithacutecerebralinfarctionwithin４８hoursofacutecerebralinfarctionwererandomlydividedintotwogroups,fourpatientswithsinglesalivaacid(１４３cases)andplaＧcebogroup(１４３cases)andplacebogroup(cases)．Resultsthecurativeeffectofthetreatmentgroupwasbetterthanthatofthecontrolgroup,thedifferencewassignificant(P＜０．００１);the２groupshadnoseriousadverseevents．ConclusionfourofthesinglesalivaryacidissafeandeffectiveinthetreatmentofacutecerebralinfarctiKoeny．wordsKeywordsFourofthepatientswithacutecerebralinfarctioninthetreatmentofacutecerebralinfarctionmonosialotetrahexosylganglioside(GM１)AcutecerebralinfarctionEfficiency;SafetyDrugTherapy中图分类号R７４３文献标识码B文章编号１００８－６３１５(２０１５)１２－０５４１－０２
出版日期
2015年12月22日（中国期刊网平台首次上网日期，不代表论文的发表时间）
