摘要
[摘要 ] 目的 探讨舍曲林合并喹硫平治疗强迫症的疗效和安全性。 方法 选取我院在 2018年 12月～ 2019年 6月中收治的强迫症患者 100例，按照随机分配的原则分为治疗组和对照组，每组患者为 50例。其中对照组患者采用舍曲林药物进行治疗，而治疗组患者采用舍曲林合并喹硫平进行治疗。治疗 8周后对比两组患者临床疗效。 结果 经过治疗，两组患者的耶鲁布朗强迫量表、简明精神病评价量表以及汉密尔顿焦虑量表评分显著低于治疗前，且治疗组患者下降优于对照组，差异具有统计学意义（ P<0.05）。 结论 对于强迫症患者采用舍曲林合并喹硫平治疗的效果好于单独使用舍曲林药物，值得在临床上广泛推广和应用。
[关键词 ] 舍曲林；喹硫平；强迫症；临床效果
[Abstract] Objective To explore the efficacy and safety of sertraline combined with quetiapine in the treatment of obsessive-compulsive disorder. Methods 100 patients with obsessive-compulsive disorder admitted to our hospital from December 2018 to June 2019 were randomly divided into treatment group and control group, with 50 patients in each group. The control group was treated with sertraline, while the treatment group was treated with sertraline combined with quetiapine. After 8 weeks of treatment, the clinical effects of the two groups were compared. Results after treatment, the scores of the two groups were significantly lower than those before treatment (P < 0.05). Conclusion sertraline combined with quetiapine is better than sertraline alone in the treatment of obsessive-compulsive disorder, which is worth popularizing and applying in clinical practice.
出版日期
2020年04月20日（中国期刊网平台首次上网日期，不代表论文的发表时间）
