摘要
Thehydrophilicityofsiliconehydrogelsusedassoftcornealcontactlensplaysanimportantroleinwearingcomfort.Inordertoenhancehydrophilicityandproteinresistance,siliconehydrogelmembranesweremodifiedbyatmosphericpressureglowdischargeplasma(APGDP)inducedsurfacegraftpolymerizationofN-vinylpyrrolidone(NVP)andpoly(oligoethyleneglycolmethylethermethacrylate)(PEGMA)inthispaper.XPSanalysisdemonstratedthesuccessofgraftpolymerizationofNVPandPEGMAontothesurfaceofsiliconehydrogelmembranes.Thehydrophilicityofsiliconehydrogelswascharacterizedbythemeasurementofwatercontactangle(WCA).TheresultshowedthatNVPgraftedsiliconehydrogelhastheWCAofabout68°andPEGMAgraftedsiliconehydrogelhasthelowestWCAofabout62°,whilethepristinesiliconehydrogelishydrophobicwiththeWCAofabout103°.Proteinresistanceofsiliconehydrogelswasinvestigatedbythemethodofbicinchoninicacidassayusingbovineserumalbumin(BSA)asamodel.It'sfoundthatthegraftedsiliconehydrogelhasasignificantimprovementofproteinresistance,andPEGMAgraftingismoreefficientforthereductionofproteinadsorptionthanNVPgrafting.ThesiliconehydrogelmembranesgraftedwithNVPandPEGMAaregoodcandidatesofsoftcornealcontactlenses.
出版日期
2010年04月14日（中国期刊网平台首次上网日期，不代表论文的发表时间）
