摘要
Outdoorairpollutionisaknownriskfactorformortalityandmorbidity.Thetypeofairpollutantmostreliablyassociatedwithdiseaseisparticulatematter(PM),especiallyfinerparticulatematterthatcanreachdeeperintothelungslikePM_(2.5)(particulatematterdiameter<2.5μm).SomesubpopulationsmaybeparticularlyvulnerabletoPMpollution.Thisreviewfocusesononesubgroup,long-termstrokesurvivors,andtheemergingevidencesuggestingthatsurvivorsofastrokemaybeatahigherriskfromthedeleteriouseffectsofPMpollution.Whilethemechanismsformortalityarestillunderdebate,long-termstrokesurvivorsmaybevulnerabletosimilarmechanismsthatunderliethewell-establishedassociationbetweenPMpollutionandcardiovasculardisease.Thefactthatlong-termstrokesurvivorsofischemic,butnothemorrhagic,strokesappeartobemorevulnerabletotheriskofdeathfromhigherPMpollutionmayalsobolstertheconnectiontoischemicheartdisease.SurvivorsofanischemicstrokemaybemorevulnerabletodyingfromhigherconcentrationsofPMpollutionthanthegeneralpopulation.TheclinicalimplicationsofthisassociationsuggestthatreducedexposuretoPMpollutionmayresultinfewerdeathsamongststrokesurvivors.
出版日期
2017年03月13日(中国期刊网平台首次上网日期,不代表论文的发表时间)