MODIFICATION OF TRYPTOPHAN RESIDUES OF IgGRF AND ITS EFFECT ON THE ADSORPTION CAPACITY

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摘要 TryptophanresiduesofIgGRFfromrheumatoidarthritispatientweremodifiedwithN-Bromosuccinimide(NBS)andtheproductofmodificationwascharacterizedbyUV-spectrum,FluorescenceemissionspectrumandCD-spectrum.ThecorrespondingadsorptioncapacityofimmobilizedssDNAimmunoadsorbentforIgGRFwasenhancedfrom46%to86%,ThisresultindicatesthetryptophanresidueisessentialfortheinteractionbetweenssDN,AandIgGRF.andionic-bondingplaysanimportantroleinadsorption.
机构地区 不详
出版日期 2002年01月11日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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