摘要
Theprolongationoflifeexpectancyandthedrasticreductionoffertilityratearetheprimarycauseofanagingworld.Itisprojectedthattheelderly(above65)willincreasewithinthenext25yearsby82%,whereasthenewbornonlyby3%.Despitetheenormousmedicalprogressduringthepastfewdecades,thelastyearsoflifearestillaccompaniedbyincreasingillhealthanddisability.Theabilitytomaintainactiveandindependentlivingforaslongaspossibleisacrucialfactorforaginginhealthanddignity.Therefore,thepromotionofhealthyagingandthepreventionofdisabilityinmen,mustassumeacentralroleinmedicalresearchandmedicalpracticeaswellasintheformulationofnationalhealthandsocialpolicies.Effectiveprogramspromotinghealthandagingwillensureamoreefficientuseofhealthandsocialservicesandimprovethequalityoflifeinolderpersonsbyenablingthemtoremainindependentandproductive.Themostimportantanddrasticgenderdifferencesinagingarerelatedtoorgansandorsystemsdependantorinfluencedbyreproductivehormones.Indistinctiontothecourseofreproductiveaginginwomen,withtherapiddeclineinsexhormonesandexpressedbythecessationofmenses,agingmenexperienceaslowandcontinuousdeclineofhormones.Thisdeclineinendocrinefunctioninvolves:Adecreaseoftestosterone,dehydroepiandrosterone(DHEA),oestrogens,thyroidstimulatinghormone(TSH),growthhormone(GH),insulin-likegrowthfactor-1(IGF-1),andmelatonin.ThisdecreaseisconcomitantwithanincreaseofLHandFSH.Inadditionsexhormonebindingglobulin's(SHBG)increasewithageresultinginfurtherloweringtheconcentrationsoffreebiologicallyactiveandrogens.Interventionssuchashormonereplacementtherapymayprevent,delayoralleviatethedebilitatingconditionswhichmayresultfromsecondarypartialendocrinedeficiency.Primaryandsecondarypreventivestrategiessuchasthepromotionofasafeenvironment,healthylifestyleincludingp
出版日期
2001年03月13日（中国期刊网平台首次上网日期，不代表论文的发表时间）
