酪酸梭菌活菌散治疗小儿消化不良性腹泻的临床效果观察

摘要 　　摘要：目的  观察酪酸梭菌活菌散在治疗小儿消化不良性腹泻患儿中的应用疗效。方法  选取 2017年 8月～ 2019年 6月 我院收治的小儿消化不良性腹泻患儿84例，按随机数字表法分为两组，各 42例。观察组给予酪酸梭菌活菌散药物联合醒脾养儿颗粒医治，对照组单独给予醒脾养儿颗粒药物医治，比较两组总有效率、症状改善时间、不良反应发生率。结果  治疗后，观察组总有效率明显高于对照组（ P<0.05）。观察组患儿腹泻、腹胀、腹痛消失时间、大便性状改变时间均短于对照组（ P<0.05） ;观察组患儿大便次数小于对照组（ P<0.05） ;观察组用药后不良反应发生率为 7.14%，低于对照组的 16.67%，差异有统计学意义（ P<0.05）。结论  在小儿消化不良性腹泻患儿中给予酪酸梭菌活菌散联合醒脾养儿颗粒医治效果较好，改善腹泻症状，用药安全性较高。  　　关键词：酪酸梭菌活菌散 ;小儿消化不良性腹泻 ;醒脾养儿颗粒   　 Abstract: Objective To observe the effect of Clostridium butyricum powder in the treatment of children with dyspepsia diarrhea. Methods from August 2017 to June 2019, 84 children with dyspepsia diarrhea were selected and divided into two groups according to the random number table, 42 cases in each group. The observation group was treated with Clostridium butyricum powder combined with Xingpi Yanger granules, while the control group was treated with Xingpi Yanger granules alone. The total effective rate, symptom improvement time and adverse reaction rate of the two groups were compared. Results after treatment, the total effective rate of the observation group was significantly higher than that of the control group (P < 0.05). The time of diarrhea, abdominal distention, disappearance of abdominal pain and change of stool characteristics in the observation group were shorter than those in the control group (P < 0.05); the frequency of stool in the observation group was shorter than that in the control group (P < 0.05); the incidence of adverse reactions in the observation group was 7.14%, lower than 16.67% in the control group (P < 0.05). Conclusion: the curative effect of Clostridium butyricum combined with Xingpi Yanger granule is better in children with dyspepsia diarrhea. It can improve the symptoms of diarrhea and has a high safety.