简介：Objective:Establishnormativedatafortympanicelectrocochleography(TMECochG)parametersinnormalhearingadultswithoutMeniere'sdisease's(MD)symptoms.DescribeTMECochGvariablesthathelptodistinguishnormalfromMDears.Materialandmethods:Weenrolled100subjects(N?200ears),59females,agedbetween19and71yearsfrom09/2010to04/2014.Inclusioncriteria:normalotomicroscopy,hearingthresholds25dBnHLfrom250to4000Hz,normaltympanogram,nosymptomsofMDaccordingtotheAAO-HNS1995criteriaandGibson'sscore<7.Weexcludedsubjectswithdizziness,auralfullnessorothersymptomsofendolymphatichydrops.Thefollowingparameterswereanalyzed:SP/APamplituderatio,SP/AParearatioandthedifferencebetweenAPlatencywithrarefactionandcondensationstimuli.Results:Therewasnosignificantdifferencebetweenrightandleftears(Intraclasscorrelationcoefficient<0.6).SP/APamplituderatiovariedbetween0.084and0.356andSP/AParearatiobetween0.837and1.671(percentiles5and95).TheAPlatencydifferencetorarefactionandcondensationclickswasbetween0.0and0.333ms.Conclusion:NormativedataforTMECochGparameterswereestablishedin100normalhearingsubjectswithoutMD.Thesedatacanbeusedtodistinguishnormalfrompathologicalfindingsandinfollow-upofMDpatients.

简介：Objective:Electrocochleography(ECochG)isvaluabletodiagnoseMeniere'sdiseaseobjectively.TheaimofthepresentstudywastoprovidepreliminarynormativedataforECochGamongAsianadults.Theinfluencesofethnicity(MalayversusChinese)andgenderonECochGresultswerealsostudied.Methods:Twenty-twoMalayadults(10menand12women)andtwentyChineseparticipants(10menand10women)agedbetween20and49yearsparticipatedinthisstudy.ExtratympanicECochG(ET-ECochG)wasrecordedaccordingtostandardnon-invasiveprocedure.Summatingpotential(SP)amplitude,actionpotential(AP)amplitudeandSP/APratiowereanalyzedaccordingly.Results:ET-ECochGresultswerefoundtobecomparablebetweenleftandrightears(p>0.05).NonotabledifferencesinET-ECochGresultswerefoundbetweenMalayandChinesegroups(p>0.05).NosignificantinfluenceofgenderonET-ECochGoutcomeswasalsonoted(p>0.05).ThederivednormativedataforAsianadults(84ears)areconsistentwithpreviousreports.Conclusion:ThepresentstudyprovidespreliminarynormativedataforET-ECochGamongAsianadults.TheECochGcomponentsdonotappeartobeinfluencedbyeitherethnicityorgender.ThederivednormativedatacanbeusedforclinicalapplicationsandasthereferenceforfuturestudiesinvolvingAsianpopulation.