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简介：Objective:Population-basedcancerregistrationdatain2012fromallavailablecancerregistriesinHenanprovincewerecollectedbyHenanOfficeforCancerResearchandControl.ThenumbersofnewcancercasesandcancerdeathsinHenanprovincewithcompiledcancerincidenceandmortalityrateswereestimated.Methods:In2015,allregistries'datainHenanprovincewerequalifiedforthenationalcancerregistryannualreportin2012.Thepooleddatawerestratifiedbyarea(urban/rural),gender,agegroup(0,1-4,5-9,10-14,…,85+)andcancertype.Newcancercasesanddeathswereestimatedusingage-specificratesandcorrespondingpopulationofHenanprovincein2012.TheChinesecensusdatain2000andSegi'spopulationwereappliedforage-standardizedrates.Alltherateswereexpressedper100,000person-years.Results:Qualified19cancerregistries(4urbanand15ruralregistries)covered16,082,688populationsofHenanprovincein2012.Thepercentageofcaseswithmorphologicallyverified(MV%)anddeathcertificateonlycases(DCO%)were69.84%and2.30%,respectively,andthemortalitytoincidencerateratio(M/I)was0.64.Itwasestimatedthattherewere248,510newcancercasesand158,630cancerdeathsinHenanprovincein2012.Theincidenceratewas266.17/100,000(288.61/100,000inmalesand241.86/100,000infemales),theage-standardizedincidenceratesbyChinesestandardpopulation(ASIRC)andbyworldstandardpopulation(ASIRW)were208.95/100,000and206.41/100,000withthecumulativeincidencerate(0-74yearsold)of24.30%.Thecrudeincidencerateinurbanareaswashigherthanthatinruralareas.However,afteradjustedbyage,thecancerincidencerateinruralwashigherthanthatinurbanareas.ThecrudemortalityofallcancersinHenanprovincewas169.90/100,000(201.23/100,000inmalesand135.95/100,000infemales).Theage-standardizedmortalityratesbyChinesestandardpopulation(ASMRC)andbyworldstandardpopulation(ASMRW)were131.20/100,000and130.80/100,000,respect

简介：Objective:Population-basedcancerregistrationdatain2012fromallavailablecancerregistriesinGansuprovincewerecollectedbytheCentralCancerRegistryofGansu.ThenumbersofnewcancercasesandcancerdeathsinGansuprovincewithcompiledcancerincidenceandmortalityrateswereestimated.Methods:In2015,datafrom7registriesinGansuprovincewerequalified.Thepooleddatawerestratifiedbyarea(urban/rural),gender,agegroup(0,1-4,5-9,10-14,…,85+)andcancertype.Newcancercasesanddeathswereestimatedusingage-specificratesandcorrespondingpopulationofGansuprovincein2012.TheChinesecensusdatain2000andSegi'spopulationwereappliedforage-standardizedrates.Alltherateswereexpressedper100,000person-years.Results:Qualified7cancerregistries(3urbanand4ruralregistries)covered2,956,560populationsofGansuprovincein2012.Thepercentageofcasesmorphologicallyverified(MV%)anddeathcertificate-onlycases(DCO%)were72.41%and1.65%,respectively,andthemortalitytoincidencerateratio(M/I)was0.63.Itwasestimatedthattherewere575,600newcancercasesand331,300cancerdeathsinGansuprovincein2012.Theincidenceratewas223.29/100,000(244.14/100,000inmalesand201.50/100,000infemales),theage-standardizedincidenceratesbyChinesestandardpopulation(ASIRC)andbyworldstandardpopulation(ASIRW)were208.95/100,000and206.41/100,000withthecumulativeincidencerate(0-74yearsold)of22.49%.Thecrudeincidencerateinurbanareaswasequaltothatinruralareas.However,afteradjustedbyage,thecancerincidencerateinurbanwasthesameasthatofruralareas.ThecrudemortalityinGansuprovincewas128.54/100,000(135.04/100,000inmalesand124.43/100,000infemales),theage-standardizedmortalityratesbyChinesestandardpopulation(ASMRC)andbyworldstandardpopulation(ASMRW)were109.54/100,000and108.44/100,000,respectively,andthecumulativemortalityrate(0-74yearsold)was12.91%.Thecrudecancer

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简介：Objective:Population-basedcancerregistrationdatain2012fromallavailablecancerregistriesinShandongprovincewerecollectedbyShandongCenterforDiseaseControlandPrevention(SDCDC).SDCDCestimatedthenumbersofnewcancercasesandcancerdeathsinShandongprovincewithcompiledcancerincidenceandmortalityrates.Methods:In2015,therewere21cancerregistriessubmitteddataofcancerincidenceanddeathsoccurredin2012.AllthedatawerecheckedandevaluatedbasedontheNationalCentralCancerRegistry(NCCR)criteriaofdataquality.Qualifieddatafrom15registrieswereusedforcancerstatisticsanalysisasprovincialestimation.Thepooleddatawerestratifiedbyarea(urban/rural),gender,agegroup(0,1-4,5-9,10-14,…,85+years)andcancertype.Newcancercasesanddeathswereestimatedusingage-specificratesandcorrespondingprovincialpopulationin2012.TheChinesecensusdatain2000andSegi'spopulationwereappliedforage-standardizedrates.Alltherateswereexpressedper100,000person-year.Results:Qualified15cancerregistries(4urbanand11ruralregistries)covered17,189,988populations(7,486,039inurbanand9,703,949inruralareas).Thepercentageofcasesmorphologicallyverified(MV%)anddeathcertificate-onlycases(DCO%)were66.12%and2.93%,respectively,andthemortalitytoincidencerateratio(M/I)was0.60.Atotalof253,060newcancercasesand157,750cancerdeathswereestimatedinShandongprovincein2012.Theincidenceratewas263.86/100,000(303.29/100,000inmales,223.23/100,000infemales),theage-standardizedincidenceratesbyChinesestandardpopulation(ASIRC)andbyworldstandardpopulation(ASIRW)were192.42/100,000and189.50/100,000withthecumulativeincidencerate(0-74yearsold)of22.07%.Thecancerincidence,ASIRCandASIRWinurbanareaswere267.64/100,000,195.27/100,000and192.02/100,000comparedto262.32/100,000,191.26/100,000and188.48/100,000inruralareas,respectively.Thecancermortalitywas164.47/100,

简介：Objective:Toestimatethecancerincidenceandmortalityin2012inGuangdongprovincebyanalyzingthecancerdataofselectedpopulation-basedcancerregistriesinGuangdongprovincein2012.Methods:Eightofninepopulation-basedcancerregistriessubmittedcancerdatatotheGuangdongProvincialCentreforDiseaseControlandPrevention(GuangdongCDC),whosedatametthedataqualitycriteriawereincludedforanalysis.Thestatisticsofselectedregistries,stratifiedbyareas,gender,ageandcancertypes,wereusedtoestimatethecancerincidenceandmortalityin2012inGuangdongprovinceaccordingtothepopulationdatainGuangdongprovince.Segi'spopulationandthenationalcensuspopulationin2000wereusedforcalculatingtheage-standardizedrates(ASR).Results:Atotalof15,084,942people,accountedfor17.47%ofallpopulationinGuangdongprovince,werecoveredin8selectedpopulation-basedcancerregistriesin2012.Thepercentageofcasesmorphologicallyverified(MV%)andthepercentageofdeathcertificate-onlycases(DCO%)were72.84%and0.87%,respectively,andthemortality/incidence(M/I)ratiowas0.56.Itwasestimatedthattherewere211,300newcancercasesand117,300cancerdeaths.Theincidencecruderate(CR),theASRbyChinesestandardpopulation(ASRC)andbyworldstandardpopulation(ASRW),andtheaccumulatedrate(AR)(0-74years)were250.20/100,000(265.39/100,000inmales,234.29/100,000infemales),207.04/100,000,201.34/100,000and22.91%,respectively,inGuangdongprovincein2012.TheincidenceCRandASRCwere267.25/100,000and221.43/100,000inurbanareas,and215.51/100,000and178.77/100,000inruralareas,respectively.ThedeathCR,ASRC,ASRWandAR(0-74years)were148.44/100,000(190.95/100,000inmales,105.06/100,000infemales),103.73/100,000,102.44/100,000and11.68%,respectively,inGuangdongprovincein2012.ThedeathCRandASRCwere164.57/100,000and105.46/100,000inurbanareas,and124.63/100,000and99.97/100,000inruralareas,respectivel

简介：AbstractBackground:Colorectal cancer (CRC) is the fourth cause of cancer death in China. We aimed to provide national and subnational estimates and changes of CRC premature mortality burden during 2005-2020.Methods:Data from multi-source on the basis of the national surveillance mortality system were used to estimate mortality and years of life lost (YLL) of CRC in the Chinese population during 2005-2020. Estimates were generated and compared for 31 provincial-level administrative divisions in China.Results:Estimated CRC deaths increased from 111.41 thousand in 2005 to 178.02 thousand in 2020; age-standardized mortality rate decreased from 10.01 per 100,000 in 2005 to 9.68 per 100,000 in 2020. Substantial reduction in CRC premature mortality burden, as measured by age-standardized YLL rate, was observed with a reduction of 10.20% nationwide. Marked differences were observed in the geographical patterns of provincial units, and they appeared to be obvious in areas with higher economic development. Population aging was the dominant driver which contributed to the increase in CRC deaths, followed by population growth and age-specific mortality change.Conclusions:Substantial discrepancies were observed in the premature mortality burden of CRC across China. Targeted considerations were needed to promote a healthy lifestyle, expand cost-effective CRC early screening and diagnosis, and improve medical treatment to reduce CRC mortality among high-risk populations and regions with inadequate healthcare resources.

简介：DuringGHtherapyfor2.3-9.6years,maleadult-onsetGH-deficientpatientswithadiagnosisofanonfunctioningadenomahavenoincreasedall-causemortality.However,womenwithadult-onsetGHdeficiency(GHD)arestillatslightlyhigherrisk.Thisgeneralimprovementinmortalityisduetoamorecontemporaryregimenofcardiovasculardrugs,arefinementofsurgicalprocedures,besidestheintroductionofGHtherapyimprovedhormonereplacementregimenswithloweredglucocorticoidreplacement,updatedapproachesofsexsteroidsforwomen,andlessuseofcranialradiotherapy.Theunderlyingdiseaseisthemostimportantpredictorformortality:eg,acraniopharyngioma,malignantcausesofhypopituitarism,previousCushing'sdisease,andthepresenceofdiabetesinsipidus/

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简介：Objective:ThisstudyestimatesthenumbersofnewcancercasesandcancerdeathsinHebeiprovinceusingincidenceandmortalitydatafrom9population-basedcancerregistriesin2012.Methods:Thedataofnewdiagnosedcancercasesandcancerdeathsin2012werecollectedfrom9population-basedcancerregistriesofHebeiprovincein2015.AllthedatamettheNationalCentralCancerRegistryofChina(NCCR)criteriaofdataquality.Thepooleddataanalysiswasstratifiedbyareas(urban/rural),gender,agegroup(0,1-4,5-9,10-14,…,85+)andcancertype.NewcancercasesanddeathsinHebeiprovincewereestimatedusingage-specificratesandcorrespondingprovincialpopulationin2012.The10mostcommoncancersindifferentgroupsandthecumulativerateswerecalculated.Chinesepopulationcensusin2000andSegi'spopulationwereusedforage-standardizedincidence/mortalityrates.Results:Allcancerregistriescovered4,986,847populations,6.84%ofHebeiprovincialpopulation(2,098,547inurbanand2,888,300inruralareas).Thepercentageofcasesmorphologicallyverified(MV%)anddeathcertificate-onlycases(DCO%)were76.40%and4.72%,respectively.Themortalitytoincidencerateratio(M/I)was0.64.In2012,itisestimatedthattherewereabout187,900newdiagnosedcancercasesand119,800cancerdeathsinHebeiprovince.Theincidencerateofcancerwas258.12/100,000(275.75/100,000inmales,239.78/100,000infemales),andtheage-standardizedincidenceratesbyChinesestandardpopulation(ASIRC)andbyworldstandardpopulation(ASIRW)were210.65/100,000and208.50/100,000,withthecumulativeincidencerates(0-74yearsold)of24.46%.ThecancerincidenceandASIRCwere256.99/100,000and211.32/100,000inurbanareasand258.94/100,000and209.99/100,000inruralareas,respectively.Thecancermortalityratewas164.63/100,000(201.85/100,000inmales,125.92/100,000infemales).AgestandardizedmortalityratesbyChinesestandardpopulation(ASMRC)andbyworldstandardpopulation(ASMRW)w

简介：Objective:ToprovideanoverviewoftheincidenceandmortalityoffemalebreastcancerforcountriesintheAsia-Pacificregion.Methods:Statisticalinformationaboutbreastcancerwasobtainedfrompubliclyavailablecancerregistryandmortalitydatabases(suchasGLOBOCAN),andsupplementedwithdatarequestedfromindividualcancerregistries.Ratesweredirectlyage-standardisedtotheSegiWorldStandardpopulationandtrendswereanalysedusingjoinpointmodels.Results:Breastcancerwasthemostcommontypeofcanceramongfemalesintheregion,accountingfor18%ofallcasesin2012,andwasthefourthmostcommoncauseofcancer-relateddeaths(9%).AlthoughincidenceratesremainmuchhigherinNewZealandandAustralia,rapidrisesinrecentyearswereobservedinseveralAsiancountries.Largeincreasesinbreastcancermortalityratesalsooccurredinmanyareas,particularlyMalaysiaandThailand,incontrasttostabilisingtrendsinHongKongandSingapore,whiledecreaseshavebeenrecordedinAustraliaandNewZealand.Mortalitytrendstendedtobemorefavourableforwomenagedunder50comparedtothosewhowere50yearsorolder.Conclusion:ItisanticipatedthatincidenceratesofbreastcancerindevelopingcountriesthroughouttheAsia-Pacificregionwillcontinuetoincrease.Earlydetectionandaccesstooptimaltreatmentarethekeystoreducingbreastcancerrelatedmortality,butculturalandeconomicobstaclespersist.Consequently,thechallengeistocustomisebreastcancercontrolinitiativestotheparticularneedsofeachcountrytoensurethebestpossibleoutcomes.

简介：AbstractBackground:Few studies have assessed the relationship between multimorbidity patterns and mortality risk in the Chinese population. We aimed to identify multimorbidity patterns and examined the associations of multimorbidity patterns and the number of chronic diseases with the risk of mortality among Chinese middle-aged and older adults.Methods:We used data from the China Kadoorie Biobank and included 512,723 participants aged 30 to 79 years. Multimorbidity was defined as the presence of two or more of the 15 chronic diseases collected by self-report or physical examination at baseline. Multimorbidity patterns were identified using hierarchical cluster analysis. Cox regression was used to estimate the associations of multimorbidity patterns and the number of chronic diseases with all-cause and cause-specific mortality.Results:Overall, 15.8% of participants had multimorbidity. The prevalence of multimorbidity increased with age and was higher in urban than rural participants. Four multimorbidity patterns were identified, including cardiometabolic multimorbidity (diabetes, coronary heart disease, stroke, and hypertension), respiratory multimorbidity (tuberculosis, asthma, and chronic obstructive pulmonary disease), gastrointestinal and hepatorenal multimorbidity (gallstone disease, chronic kidney disease, cirrhosis, peptic ulcer, and cancer), and mental and arthritis multimorbidity (neurasthenia, psychiatric disorder, and rheumatoid arthritis). During a median of 10.8 years of follow-up, 49,371 deaths occurred. Compared with participants without multimorbidity, cardiometabolic multimorbidity (hazard ratios [HR] = 2.20, 95% confidence intervals [CI]: 2.14-2.26) and respiratory multimorbidity (HR= 2.13, 95% CI:1.97-2.31) demonstrated relatively higher risks of mortality, followed by gastrointestinal and hepatorenal multimorbidity (HR= 1.33, 95% CI:1.22-1.46). The mortality risk increased by 36% (HR= 1.36, 95% CI: 1.35-1.37) with every additional disease.Conclusion:Cardiometabolic multimorbidity and respiratory multimorbidity posed the highest threat on mortality risk and deserved particular attention in Chinese adults.

简介：AbstractBackground:Whether there is an association between serum uric acid (SUA) level and risk of mortality in the general population remains unclear. Based on the China National Survey of Chronic Kidney Disease linked to mortality data, a population-based cohort study was performed to investigate the association between SUA level and all-cause mortality, cardiovascular disease (CVD) mortality, and cancer mortality in China.Methods:The survival status of participants in the cross-sectional survey was identified from January 1, 2006 to December 31, 2017. Only 33,268 individuals with complete SUA data among the 47,204 participants were included in the analysis. We determined the rates of all-cause mortality, CVD mortality, and cancer mortality. We used Cox proportional hazards regression models to evaluate the effect of the SUA level on mortality.Results:During a total of 297,538.4 person-years of follow-up, 1282 deaths occurred. In the Cox proportional hazards regression model, the rate of all-cause mortality, CVD mortality, and cancer mortality had a U-shaped association with SUA levels only in men, whereas no significant associations were detected in women. For all-cause mortality in men, the multivariable-adjusted hazard ratios (HRs) in the first, second, and fourth quartiles compared with the third quartile were 1.31 (95% confidence interval [CI] 1.04-1.67), 1.17 (95% CI 0.92-1.47), and 1.55 (95% CI 1.24-1.93), respectively. For CVD mortality, the corresponding HRs were 1.47 (95% CI 1.00-2.18), 1.17 (95% CI 0.79-1.75), and 1.67 (95% CI 1.16-2.43), respectively. For the cancer mortality rate, only a marginally significant association was detected in the fourth quartile compared with the third quartile with an HR of 1.43 (95% CI 0.99-2.08).Conclusions:The association between SUA and mortality differed by sex. We demonstrated a U-shaped association with SUA levels for all-cause and CVD mortalities among men in China.

简介：Objective:ToanalyzetheincidenceandmortalityratesoflungcancerinChinafrom2008to2012.Methods:IncidentanddeathcasesoflungcancerwereretrievedfromtheNationalCentralCancerRegistry(NCCR)databasecollectingfrom135cancerregistriesinChinaduring2008-2012.Thecrudeincidenceandmortalityratesoflungcancerwerecalculatedbyarea(urban/rural),region(eastern,middle,western),genderandagegroup(0,1-4,5-9,…,85+).Chinacensusin2000andSegi’sworldpopulationwereappliedforagestandardizedrates.JoinPoint(Version4.5.0.1)modelwasusedfortimetrendanalysis.Results:Thecrudeincidencerateoflungcancerwas54.66/100,000whichrankedthefirstinoverallcancers.Theage-standardizedincidenceratesbyChinapopulation(ASIRC)andbyWorldpopulation(ASIRW)were35.13/100,000and34.86/100,000,respectively.ThecrudemortalityoflungcancerinChinawas45.60/100,000anditwasthefirstcauseofcancer-relateddeathinoverallcancers.Theage-standardizedmortalityratesbyChinesestandardpopulation(ASMRC)andbyworldstandardpopulation(ASMRW)were28.57/100,000and28.22/100,000,respectively.Incidenceandmortalityratesoflungcancerwerehigherinmalesthaninfemalesandhigherinurbanareasthaninruralareas.Easternareashadthehighestincidenceandmortalityratesfollowedbymiddleandwesternareas.Incidenceandmortalityratesoflungcancerretainedlowlevelinagegroupsbefore40yearsoldbutincreasedgreatlyafterandpeakedinagegroupof80-84.During2003-2012,thetemporaltrendoftheincidencerateoflungcancerinbothsexesinChinawasgeneralstable(P<0.05).Thelungcancerincidencerateincreasedby0.71%peryearinfemales(P<0.05)and2.26%peryearinruralareas(P<0.05).Themortalityrateoflungcancerdecreasedslightlyannuallyduring2003-2012inChina(P>0.05).Inurbanareas,itdeclinedby0.76%peryear(P<0.05),butroseby2.09%peryear(P<0.05)inruralareas.Conclusions:Appropriatetargetedprevention,earlydetectionandtreatment

简介：Modelinglog-mortalityratesonO-UtypeprocessesandforecastinglifeexpectanciesareexploredusingU.S.data.IntheclassicLee-Cartermodelofmortality,thetimetrendandtheage-specificpatternofmortalityoveragegrouparelinear,thisisnotthefeatureofmortalitmodel.Toavoidthisdisadvantage,O-Utypeprocesseswillbeusedtomodelthelog-mortalityinthispaper.Infact,thismodelisanAR(1)process,butwithanonlineartimedriftterm.BasedonthemortalitydataofAmericafromHumanMortalitydatabase(HMD),mortalityprojectionconsistentlyindicatesapreferenceformortalitywithO-UtypeprocessesoverthosewiththeclassicalLee-Cartermodel.Bymeansofthismodel,thelowboundsofmortalityratesateveryagearegiven.Therefore,lengtheningofmaximumlifeexpectanciesspanisestimatedinthispaper.

简介：Objective:LivercancerisoneofthemostcommoncancersandmajorcauseofcancerdeathsinChina,whichaccountsforover50%ofnewcasesanddeathsworldwide.Thesystematiclivercancerstatisticsincludingofprojectionthrough2030couldprovidevaluableinformationforpreventionandcontrolstrategiesinChina,andexperienceforothercountries.Methods:TheburdenoflivercancerinChinain2014wasestimatedusing339cancerregistries’dataselectedfromChineseNationalCancerCenter(NCC).Incidentcasesof22cancerregistrieswereappliedfortemporaltrendsfrom2000to2014.Theburdenoflivercancerthrough2030wasprojectedusingage-period-cohortmodel.Results:About364,800newcasesoflivercancer(268,900malesand95,900females)occurredinChina,andabout318,800livercancerdeaths(233,500malesand85,300females)in2014.WesternregionsofChinahadthehighestincidenceandmortalityrates.Incidenceandmortalityratesdecreasedbyabout2.3%and2.6%peryearduringtheperiodof2000-2014,respectively,andwoulddecreasebymorethan44%between2014and2030inChina.Theyounggeneration,particularlyforthoseagedunder40years,showedafasterdowntrend.Conclusions:Basedontheanalysis,incidenceandmortalityratesoflivercancerareexpectedtodecreasethrough2030,buttheburdenoflivercancerisstillseriousinChina,especiallyinruralandwesternareas.MostcasesoflivercancerinChinacanbepreventedthroughvaccinationandmorepreventioneffortsshouldbefocusedonhighriskgroups.

简介：AbstractBackground:According to the Independent High-level Commission on Non-communicable Diseases (NCD) of the World Health Organization (WHO), global reduction in lung cancer mortality has been achieved since the year 2000, although this effect is not sufficient to reach the 30% reduction of mortality from NCDs by the year 2030, as stipulated by the United Nations Sustainable Development Goal 3.4. The objective of this study was to analyze whether the lifestyle changes implemented by the WHO at country level could have an impact on mortality from this form of cancer.Methods:WHO statistics, based on the unified mortality and causes-of-death reports of Member-State countries, were used to evaluate global lung cancer mortality trends and make comparisons and assessments of different types of community-based, country-wide interventions.Results:The lung cancer mortality decline was associated with the anti-tobacco campaign initiated by the WHO in the last 15 to 20 years. Comprehensive tobacco control remained the major and most successful lifestyle modification measure. In countries with declining lung cancer mortality, 91% of countries had decreasing tobacco prevalence in males and 82% in females. Country-wide measures to increase physical activity had a strong tendency to be better implemented in countries with declining lung cancer mortality (t = 1.79, P > 0.05). Other WHO "best-buy" lifestyle modification campaigns (diet and alcohol) had been carried out for shorter periods, and their associations with lung cancer were less strong than tobacco. There was no significant difference between countries with declining and increasing lung cancer mortality in the measures for reduction of harmful alcohol use (t= 0.92, P > 0.05) and unhealthy diet reduction measures (t= 0.84, P > 0.05).Conclusion:Following WHO "best-buys" should facilitate to move countries towards the NCD including lung cancer mortality reduction targets. Governments and communities must embrace these targets with coordinated effective action for better health.

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简介：在有长期的心失败(CHF)的病人的雄激素的浆液层次的预示的意义上的以前的研究让步了冲突结果。这研究的目的是与收缩CHF在人检验在睾丸激素和死亡的浆液集中之间的关系。175个老人的一个总数(age≥；60年)与CHF被招募。全部的睾丸激素(TT)和性荷尔蒙绑定血球素(SHBG)被测量，并且估计免费睾丸激素(水蜥)是计算的。中部的后续时间是3.46年。这些病人，17在8 下面有TT水平；nmoll−1(230 ；27有的ngdl−1),在0.225 下面的水蜥水平；nmoll−1(65 ；pgml−1)并且12有两个。用年龄特定在在我们截止指的实验室的健康的人的TT和水蜥的第十个百分位数，TT的流行和水蜥缺乏是21.7%；(38/175)并且27.4%；(48/175)分别地。TT和水蜥相反地与左室的喷射部分(LVEF)和N终端被联系支持大脑的natriuretic肽(NT-pro-BNP)(所有P<；0.01)。为根据TT和水蜥，水平看了显著地不同的累积幸存的在低、中等、高的tertiles的病人的Kaplan-Meier曲线评价(两P<；0.01由木头等级测试)。在为临床的变量的调整以后，然而，与幸存时间没有TT或水蜥层次的重要协会(OR=0.97，95%；CI：0.84-1.12，P=0.28和OR=0.92，95%；CI：0.82-1.06，P=0.14，分别地)。我们的学习证明TT和水蜥的层次通常与收缩CHF并且与疾病严厉有关在老病人被减少，但是他们不是为死亡的独立预言者。