简介：Inthisarticle,theauthorlistedalotoffactstoillustratethehealthhazardsmaybemetduringtravel,anddescribedvarioushealthproblemcausedbythehazards.Travelersmayknowthesehazardsandthentakethenecessarypreventionmeasuresthroughtravelhealthconsultation.Andthetravelersthemselvesmayassistthedoctorsindiagnosisandcurethehealthproblemrelatedtotravel.Inthiswaythetravelershealthmaybeprotected.TheauthorpointedoutthattheChinesepeopleshouldcreatetheirownenvironmentandtrainstaffforthegraduallyinitialingoftravelhealthconsultation.

简介：One-cellmouseembryosfromKMstrainandB6C3F1strainwereculturedinM16medium,inwhich2-cellblockgenerallyoccurs.EmbryosofKMstrainexhibited2-cellblock,whereasB6C3F1embryos,whichareregardedasanonblockingstrain,proceededtothe4-cellstageinourculturecondition.Itisoftenassumedthattheblockofearlydevelopmentisduetothefailureofzygoticgeneactivation(ZGA)inculturedembryos.Inthisstudyweexaminedproteinsynthesispatternsbytwo-dimensionalgelelectrophoresisof[35S]methionineradiolabeled2-cellembryos.Embryosfromtheblockingstrainandthenonblockingstrainwerecomparedintheirdevelopmentbothinvitroandinvivo.ThedetectionofTRCexpression,amarkerofZGA,at42hposthCGinKMembryosdevelopedinvitrosuggestedthatZGAwasalsoinitiatedeveninthe2-cellarrestedembryos.Nevertheless,asignificantdelayofZGAwasobservedinKMstrainascomparedwithnormallydevelopedB6C3F1embryos.AttheverybeginningofmajorZGAasearlyas36hposthCG,TRChasalreadybeenexpressedinB6C3F1embryosdevelopedinvitroandKMembryosdevelopedinvivo.Butfor2-cellblockedKMembryos,TRCwasstillnotdetectableevenat38hposthCG.Theseevidencessuggestthat2-cell-blockedembryosdoinitiateZGA,andthat2-cellblockphenomenonisduenottothedisabilityininitiatingZGA,buttoadelayofZGA.

简介：AbstractWe analyzed variations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome during a flight-related cluster outbreak of coronavirus disease 2019 (COVID-19) in Shenzhen, China, to explore the characteristics of SARS-CoV-2 transmission and intra-host single nucleotide variations (iSNVs) in a confined space. Thirty-three patients with COVID-19 were sampled, and 14 were resampled 3-31 days later. All 47 nasopharyngeal swabs were deep-sequenced. iSNVs and similarities in the consensus genome sequence were analyzed. Three SARS-CoV-2 variants of concern, Delta (n = 31), Beta (n = 1), and C.1.2 (n = 1), were detected among the 33 patients. The viral genome sequences from 30 Delta-positive patients had similar SNVs; 14 of these patients provided two successive samples. Overall, the 47 sequenced genomes contained 164 iSNVs. Of the 14 paired (successive) samples, the second samples (T2) contained more iSNVs (median: 3; 95% confidence interval [95% CI]: 2.77-10.22) than did the first samples (T1; median: 2; 95% CI: 1.63-3.74; Wilcoxon test, P = 0.021). 38 iSNVs were detected in T1 samples, and only seven were also detectable in T2 samples. Notably, T2 samples from two of the 14 paired samples had additional mutations than the T1 samples. The iSNVs of the SARS-CoV-2 genome exhibited rapid dynamic changes during a flight-related cluster outbreak event. Intra-host diversity increased gradually with time, and new site mutations occurred in vivo without a population transmission bottleneck. Therefore, we could not determine the generational relationship from the mutation site changes alone.

简介：Thegrowingcorrelationlengthpriortothemoderate-greatearthquakesoccurredinGansuProvinceanditsnearbyareasince1986hasbeenstudiedusingthemethodofsingle-linkclusteranalysis(SLC).Accordingtodifferentconditionsinthesourcearea,thecircularspatialwindowcenteredintheepicenterandtheparallelgrammicspatialwindowalongthefaultbelthavebeenselected.Theresultsshowthatthephenomenaofgrowingcorrelationlengthhavebeenobservedbeforetheearthquakesstudiedinthepaper.

简介：Thedensebroadbandseismicnetworkprovidesmorehigh-qualitywaveformthatishelpfultoimproveconstraintfocaldepthofshallowearthquake.Manyshallowearthquakesoccurringinsedimentwereregardedasinducedevents.InSichuanbasin,gasindustryandsaltminingaredependentonfluidinjectiontechniquethattriggersmicroseismicity.WeadoptedwaveforminversionmethodwithregionalrecordstoobtainfocalmechanismofanMs4.8earthquakeatChangning.TheresultsuggestedthattheChangningearthquakeoccurredataESEthrustfault,anditsfocaldepthwasabout3km.ThedepthphasesincludingteleseismicpPphaseandregionalsPLphaseshowsthatthefocaldepthisabout2km.Thestrong,shortperiodsurfacewavesuggeststhatthiseventisaveryshallowearthquake.TheamplituderatiobetweenRayleighwaveanddirectSwavewasalsousedtoestimatethesourcedepthofthemainshock.Thefocaldepth(2–4km)isfarlessthanthedepthofthesedimentarylayerthickness(6–8km)inepicentralregion.Itisclosetothedepthoffluidinjectionofsaltmining,whichmayimplythatthiseventwastriggeredbytheindustrialactivity.

简介：FLATModel是包含几原版的有限的卷代码接近改进碎片流动模拟的2D。第一，FLATModel在每个房间合并一种定期而不断被迫停的技术允许碎片流动团的连续倒塌和动员。第二，流动速度并且因而，收益应力直接与流变学的类型被联系改善边界精确性。第三，为乘火车的一条简单途径也在模型被包括分析碎片流动的基础侵蚀的效果。FLATMODEL在发生在东方比利牛斯山脉的几个事件被测试，模拟结果显示模型能代表在这块地里观察的不同特征相当好。

简介：ThemainshockandaftershocksoftheHutubiMS6.2earthquakeonDecember8,2016wererelocatedbyapplyingthedoubledifferencemethod,andwerelocated477earthquakesintheHutubiregion.Theearthquakerelocationresultsshowthattheaftershocksaredistributedintheeast-westdirectiontowardsthenorthsideofthesouthernmarginoftheJunggarBasinfault,andaremainlydistributedinthewesternregionofthemainshock.ThedistancebetweenthemainshockafterrelocationandthesouthernmarginoftheJunggarBasinfaultisobviouslyshortened.Combinedwiththefocalmechanismandthespatialdistributionofthemainshockandaftershocks,itisinferredthatthesouthernmarginoftheJunggarBasinfaultisthemainseismogenicstructureoftheHutubiearthquake.

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