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  • 简介:ZouYan,female,researcher,majoringinevidence-basedmedicine,graduatedfromWestChinaSchoolofMedicine,SichuanUniversityandgainedadegreeofMedicalDoctor.Shehadbeenengagedinclinicalworkofobstetricsandgynecologyfortenyears.Currently,sheworksasHeadofWomenClinicalLaboratoryintheScientificResearchInstituteofNationalHealthandFamilyPlanningCommission,andamasterinstructorofDepartmentofObstetricsandGynecologyinPekingUnionMedicalCollege.

  • 标签: 青少年 临床实验室 怀孕 循证医学 科学研究所 中国西部
  • 简介:1.IntroductionandMainResultSincethedefinitiononthecompleteconvergencewasintroducedbyHsuandRobbins[1],therehavebeenmanyauthorswhodevotethemselvestothestudyonthisconvergenceofiidrandomvariables,seeGut[2,3],BaiandSu[4]andLin[5].Meanwhile,somescholarshav...

  • 标签: MIXING sequence partial SUM CONVERGENCE rate
  • 简介:AbstractObjective:Mifepristone (RU486), one of the most common medications for artificial abortion, attenuates the immunoregulatory effects of progesterone. However, the specific immune regulatory mechanism of RU486 in abortion remains unknown. We intended to investigate the immunomodulatory effects of RU486 on abortion.Methods:Sixty female mice were divided into the control group (0 mg RU486) and RU486 group (2 mg/kg RU486). The uterus, peripheral blood, and spleen were obtained for isolation of specific cell types. The population and phenotype of immune cells in the decidua, peripheral blood, and spleen were analyzed using flow cytometry. Statistical differences between groups were determined using two-tailed t-test. For all statistical tests, P < 0.05 was considered statistically significant.Results:RU486 effectively induced abortion in pregnant mice, with a significantly higher number of decidual macrophages (dMφ) (control group = 25.55% ± 2.467%, RU486 group = 19.41% ± 1.423%; P < 0.05), especially the major histocompatibility complex IIhigh subset. No difference in Mφ number was observed in the spleen or peripheral blood. Moreover, the dMφ from mice with RU486-induced abortion displayed a remarkable activated phenotype, with increased expressions of inducible nitric oxide synthase, tumor necrosis factor-α, and interleukin (IL)-12 but decreased expressions of arginase-1 and IL-10. We also found elevated levels of decidual CD4+ T-cells in the RU486 group that exhibited a higher level of the proinflammatory cytokine interferon-γ and a lower level of the anti-inflammatory cytokines, IL-4 and IL-10.Conclusions:We report a new mechanism of RU486-induced abortion via the regulation of innate cell Mφ activation and the adaptive response of CD4+ T-cells present in the decidua but not the periphery.

  • 标签: Decidual CD4+ T-Cells Decidual Macrophages Induced Abortion RU486
  • 简介:在这篇论文,我们使用插件并且切基于的方法光谱在12亚洲人/美元的每日的汇率为长记忆性质测试的回归分析。结果根据插件方法证明与中国人民币的例外,所有系列可以有长记忆性质。在另一方面,结果基于Whittle方法证明那仅仅日本的日元和马来西亚ringgit可以有长记忆性质。它是著名的关于differencing参数的那推论,d,在在一个系列的结构的裂缝的存在必要可观的困难。因此,在亚洲给1997-1998的金融危机,为记忆性质的unravelling和在汇率系列的结构的裂缝的存在的进一步的测试被要求。

  • 标签: 汇兑行情 插入式方法 削成形方法 实验研究 记忆
  • 简介:Ourobjectiveisabetterunderstandingoftheroleofphysicalpropertiesofrealfluidsinthethermodynamicsofcavitationinimpurewater.Anextensiontotheclassicalhomogenousnucleationtheorysuitableformixturesispresentedinattempttoaddressthediscrepancybetweenthetheoreticalpredictionsandpracticalobservationsofcavitationratesinwateratnormaltemperatures.Theextensiontakesintoaccoutthenon-equilibrium(dissipative)effectsinvolvedinnucleiformationthroughasubstancedependentcorrectioncoefficienttobedeterminedexperimentally.Thetheoryofthermodynamicfluctuationsisappliedtoderivetheworkofformationofabubblenucleus.Thevalueofthecorrectioncoefficientisestimatedusingpreliminaryexperimentaldatafromaconvergent-divergentnozzle.Anapplicationoftheresultstothenumericalpredictionofthecavitationzonesinaradial-flowwaterpumpisshown.

  • 标签: 空化比率 均匀成核作用 液化气体 杂质 计算流体力学
  • 简介:ThegovernmentofNepalhasurgedNorwegianandUSutilitycompaniesoperatinginthecountrytoslashthepriceoftheelectricitytheyselltothestate-ownedpowerdistributor,NepalElectricityAuthority(NEA).

  • 标签: 尼泊尔 水力发电 投资 工程建设
  • 简介:TheanalysisofcelllossratesinanATMMuxwithlossprioritiesisanimportantprobleminthe-studyoftrafficcontrolinATMnetworks.Inthispaper,thelossratesofthecellswithdifferentprioritiesinanATMMuxareanalyzedbyapproximatingtheactualinputprocesswithtwo-stateMMDPandfluidflowtechnique,andtheanalyticalexpressionsoftherelationbetweenthelossratesandthebuffersizeareobtained.Simulationshowsthattheapproachissullicientlyaccurateforapplications.

  • 标签: LOSS PRIORITY mechanism Cell LOSS RATE
  • 简介:在现在的学习,旋涡在开的隧道流动被产生,跨流动的柱体在床附近水平地安装了。沉积拾起率然后下游地在隧道床上被测量用一部沉积电梯的柱体。拾起率面对旋涡指数地增加的试验性的数据表演。二种不同关系能清楚地为没有障碍的流动在拾起率和streamwise速度变化,为妨碍柱体的流动的变化和其它的最大的root-mean-square(rms)价值之间被观察。结果暗示导致旋涡的沉积拾起不能基于传统的边界层理论被解释。

  • 标签: 实验室测量 沉积物 拾取 涡流 速率 明渠流量
  • 简介:不同变化(替换)与微妙的还重要的差别当模特儿的为估计在编码蛋白质的序列之中的率采用的同义、非同义的替换的方法,它导致进化信息的不同估计。自从在指向的数据集以内的顺序变化的数量总是是无法预言的,很少注意都没为获得可靠估计被奉献给方法的比较。到我们的知识,几乎没有在关于这些不同方法的评估的文学可得到的很少信息。在这研究,我们比较了六个广泛地使用的方法并且用模仿的序列向结果提供了评估。结果显示那合并顺序特征(例如transition/transversion,偏爱和nucleotide/codon频率偏导)进方法能产出更好的性能。我们建议结论与有关或源于Ka,K分析不应该乐意地从一个方法仅仅根据结果被拉。

  • 标签: 基因序列 基因突变 蛋白 生物
  • 简介:ExperimentswerecarriedoutonavegetablefieldwithPekingcabbage(Brassicapekinensis(Lour.)Rupr.),cabbage(Brassicachinensisvar.OleiferaMakinoandnemoto),greencabbage(BrassicachinensisL.),spinach(SpinaciaoleraceaL.)andrape(BrassicacampestrisL.)tostudytheeffectsofNformsandNratesontheirgrowthandnitrateaccumulation.Theresultsindicatedthatapplicationofammoniumchloride,ammoniumnitrate,sodiumnitrateandureasignificantlyincreasedtheyieldsandnitrateconcentrationsofPekingcabbageandspinach.Althoughnosignificantdifferencewasfoundintheyieldsafterapplicationofthe4Nforms,nitrateNincreasednitrateaccumulationinvegetablesmuchmorethanammoniumN.ThevegetableyieldswerenotincreasedcontinuouslywithNrateincrease,andoversupplyofNreducedtheplantgrowth,leadingtoayielddecline.Thistrendwasalsotruefornitrateconcentrationsinsomevegetablesandatsomesamplingtimes.However,asawhole,thenitrateconcentrationsinvegetableswerepositivelycorrelatedwithNrates.Thus,additionofNfertilizertosoilwasthemajorcauseforincreasesinnitrateconcentrationsinvegetables.Nitrateconcentrationsweremuchhigherinroots,stemsandpetiolesthaninbladesatanyNrate.

  • 标签: 蔬菜生长 硝酸盐 结构 含氮比率 甘蓝
  • 简介:Recurrenteventdataoftenarisesinbiomedicalstudies,andindividualswithinaclustermightnotbeindependent.Weproposeasemiparametricadditiveratesmodelforclusteredrecurrenteventdata,whereinthecovariatesareassumedtoaddtotheunspecifiedbaselinerate.Fortheinferenceonthemodelparameters,estimatingequationapproachesaredeveloped,andbothlargeandfinitesamplepropertiesoftheproposedestimatorsareestablished.

  • 标签: 半参数模型 添加剂 事件 集群 复发 价格
  • 简介:Recurrenteventsdatawithaterminalevent(e.g.death)oftenariseinclinicalandobservationalstudies.Mostofexistingmodelsassumemultiplicativecovariateeffectsandmodeltheconditionalrecurrenteventrategivensurvival.Inthisarticle,weproposeageneraladditive-multiplicativeratesmodelforrecurrenteventdatainthepresenceofaterminalevent,wheretheterminaleventstopthefurtheroccurrenceofrecurrentevents.Basedontheestimatingequationapproachandtheinverseprobabilityweightingtechnique,weproposetwoproceduresforestimatingtheregressionparametersandthebaselinemeanfunction.Theasymptoticpropertiesoftheresultingestimatorsareestablished.Inaddition,somegraphicalandnumericalproceduresarepresentedformodelchecking.Thefinite-samplebehavioroftheproposedmethodsisexaminedthroughsimulationstudies,andanapplicationtoabladdercancerstudyisalsoillustrated.

  • 标签: 模型检查 事件 终端 乘率 环和 平均函数
  • 简介:TheeffectofQiGongreflectedbyrheoencephalographyandheartratewerestudiedinthispaper.ThefunctionalrelationshipbetweenwaveamplitudeandtheheartratesreflectedbytwoprocessesofQiGong,“JingGong”forenergyprovoca-tive,and“FaGong”forenergyreleasehavebeencomparedandanalysed.28casesofwelltrained“QiGong”practitionersvolunteerinthisstudy.Therheoencepha-

  • 标签: WAVE QI GONG THE EFFECT OF