简介:Myringitiscanbeacuteorchronic.Thoughtheycommonlypresentwitheardischargewithorwithoutpain,theetiologyandthemanagementprinciplesdiffer.Granularmyringitisgenerallyisanexternalearpathologyextendingtotympanicmembraneandpresentaspainlessotorrhea,whereasthebullousmyringitisiscommonlyassociatedwithacuteinflammationofmiddleearcleftandpresentwithsevereearpain.Thisliteraturereviewdiscussestheclinicalaswellasthetherapeuticaspectsoftheseinflammatoryconditions.
简介:BCHydrohasnowcompletedworkonstage1oftheElsiedamupgradeinVancouverlsland,Canada.Thedam,partofthe27MWAshriverhydroelectricfacilitybuiltin1958,isbeingupgradedtoresistsmajorseismicevents.Darnsafetyinvestigationshadshownthatathinlayerofsaturatedloosematerialinthemaindamatapproximatelyel326mwouldliquefyduringamajorearthquake.
简介:可扩展的标注语言(XML)为在基于万维网的应用代表并且互换数据成为了事实上的标准。并且XML看法,为指定用户的一扇虚拟窗户,广泛地被使用了。在实际系统,当他们需要通过看法更新来源数据时,用户们遇到所谓的看法更改问题。很长时间,看法更改问题是在数据库社区的一个待研究的问题。与各种各样的数据模型的开发,相应看法更改问题广泛地被研究了。在这篇论文,我们介绍看法更改问题的概念。我们调查并且比较以前的途径。特别,我们强调语义的角色。在XML上下文集中于这个问题,我们给讨论并且建议一个框架,它在看法定义时间收集语义信息。为实现这个框架的一些相关技术进一步被介绍。
简介:AbstractObjective:To study the epidemiology of leprosy in China in 2019 and give suggestions to improve future leprosy control activities.Methods:We collected leprosy data from the Leprosy Management Information System in China, which includes data from 31 Chinese provinces, autonomous regions, and municipalities, except for Hong Kong, Macao, and Taiwan. We then performed a descriptive analysis of these data.Results:A total of 464 new leprosy cases were reported nationwide in 2019, with a case detection rate of 0.033/100,000. The proportions of children younger than 15 years, multibacillary cases, and cases with World Health Organization grade 2 disability were 1.3%, 90.3%, and 21.6%, respectively. A total of 2,219 leprosy cases were registered in China by the end of 2019, giving a prevalence rate of 0.158/100,000. Fifty-six counties had a prevalence rate of more than 1/100,000, and most of them were located in Southwest China. There were 31 reported relapse cases.Conclusion:The prevalence of leprosy has improved continuously throughout China, but the southwest region is still an area of concern.
简介:Weprovideaconcisereviewofthemainepidemiologicalliteratureonfattyliver(FL)publishedbetweenJanuary2011andOctober2013.Thefindingsfromtheliteraturewillbeconsideredinlightofthealreadyavailableknowledge.WediscussthelimitationsinherentinthecategorizationofFLintonon-alcoholicandalcoholicFL,thepotentialrelevanceofFLasanindependentpredictorofcardiometabolicdisease,andrecentresearchaddressingtheroleofFLasanindependentpredictorofmortality.ThisreviewisorganizedasaseriesofanswerstorelevantquestionsabouttheepidemiologyofFL.
简介:为可勃起的机能障碍的当代的治疗通常向老人被指向并且普遍雇佣药理学或设备相关治疗选择。阴茎revascularization,用microvascular动脉绕过外科的技术,是非药理学,non-device-related,和为有被瓦克拉夫·米查尔博士首先在1973描述的可勃起的机能障碍的人的改造外科的策略。当代的阴茎revascularization尝试到‘;cure'纯arteriogenic在有在远侧的内部pudendal的动脉的闭塞的病理的年轻人的可勃起的机能障碍,对从钝骨盆、会阴或阴茎的损伤的焦点的endothelial损害第二等的普通阴茎或近似的cavernosal动脉。microvascular吻合在腹上部的施主晚辈和接受者之间被塑造背面的阴茎动脉。增加的灌注压力理论上经由穿孔被传达到cavernosal动脉从背面的动脉的分支。这篇文章将与可勃起的机能障碍,利用的当前的外科的技术和外科的结果在年轻人考察钝导致损伤的焦点的动脉的闭塞的疾病的历史,指示和pathophysiology。阴茎revascularization的当代的使用是一种逻辑、想要的治疗学的选择试图在支撑了钝骨盆、会阴或阴茎的损伤的年轻人颠倒可勃起的机能障碍。
简介:AbstractFetal growth restriction (FGR) has a prevalence of about 10% worldwide and is associated with an increased risk of perinatal mortality and morbidity. FGR is commonly caused by placental insufficiency and can begin early (<32 weeks) or in late (≥32 weeks) gestational age. A false positive antenatal diagnosis may lead to unnecessary monitoring and interventions, as well as cause maternal anxiety. Whereas a false negative diagnosis exposes the fetus to an increased risk of stillbirth and renders the pregnancy ineligible from the appropriate care and potential treatments. The clinical management of FGR pregnancies faces a complex challenge of deciding on the optimal timing of delivery as currently the main solution is to deliver the baby early, but iatrogenic preterm delivery of infants is associated with adverse short-and long-term outcomes. Early and accurate diagnosis of FGR could aid in better stratification of clinical management, and the development and implementation of treatment options, ultimately benefiting clinical care and potentially improving both short-and long-term health outcomes. The aim of this review is to present the new insights on biomarkers of placenta insufficiency, including their current and potential value of biomarkers in the prediction and prevention for FGR, and highlight the association between biomarkers and adverse outcomes in utero to explore the specific mechanism of impaired fetal growth that establish the basis for disease later in life.
简介:Rheumatoidarthritis(RA)isasystemic,autoimmunediseasethatpresentwithintra-articularandextra-articularmanifestations.AuditorysystemmaybeinvolvedduringthecourseofRAdiseaseduetonumbersofpathologies.ThelinkbetweenhearingimpairmentandRAhasbeendiscussedinthepreviousliterature.InthisstudyweprovideanupdateontheclinicalaspectofhearingimpairmentinRA.WesuggesttotesthearinginallnewlydiagnosedRApatientsatdiagnosisaswellasregularlyduringthecourseofdisease.
简介:DuringGHtherapyfor2.3-9.6years,maleadult-onsetGH-deficientpatientswithadiagnosisofanonfunctioningadenomahavenoincreasedall-causemortality.However,womenwithadult-onsetGHdeficiency(GHD)arestillatslightlyhigherrisk.Thisgeneralimprovementinmortalityisduetoamorecontemporaryregimenofcardiovasculardrugs,arefinementofsurgicalprocedures,besidestheintroductionofGHtherapyimprovedhormonereplacementregimenswithloweredglucocorticoidreplacement,updatedapproachesofsexsteroidsforwomen,andlessuseofcranialradiotherapy.Theunderlyingdiseaseisthemostimportantpredictorformortality:eg,acraniopharyngioma,malignantcausesofhypopituitarism,previousCushing'sdisease,andthepresenceofdiabetesinsipidus/