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Biochemical mechanisms of the RNA-induced silencing complex

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摘要在不到10年里自从它的开始，RNA干扰(RNAi)在生物医学的科学上有非凡的影响。RNAi被表明了到影响众多生物并且疾病小径。RNAi技术的开发和采纳是丰富的从基本loss-of-function工具，到药品的目标确认的染色体宽的屏蔽图书馆和治疗学的开发。然而，RNAiis的分子的机制理解远非完全。这简短评论的目的是在阐明加亮关键成就导致RNA的silencing建筑群并且到的生化学机制为这块地构画出主要挑战。

DOI 0dpoyorkj2/498493

作者 Zain Paroo;Qinghua Liu;Xiaodong Wang

机构地区不详

出处《细胞研究：英文版》 2007年3期

关键词 RNA诱导沉默复合物生物化学机制致活 RNA干扰 SIRNA

分类 [生物学][细胞生物学]

出版日期 2007年03月13日（中国期刊网平台首次上网日期，不代表论文的发表时间）

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来源期刊

细胞研究：英文版

细胞研究：英文版

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相关关键词

RNA诱导沉默复合物生物化学机制致活 RNA干扰 SIRNA

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