简介：Theeffectofage-relatedbonelossonthestructuralcapacityoftheproximalfemurwereinvestigatedbyFiniteElementAnalysis(FEA).Fourbonelosspatternswereconsidered.Thesewere'uniformcorticalboneloss','neckcorticalboneloss','intertrochantericcorticalboneloss'and'uniformtrabecularboneloss'.Theresultsshowthatthetwo'non-uniformcorticalboneloss'patternsaremoredangerousthanthe'uniformcorticalboneloss'pattern,andthatthecorticalbonelossinintertrochantericregionisassociatedwithagreaterreductionincorticalfailureloadthanthecorticalbonelossinthefemoralneck.Thetrabecularbonelosscausesalimiteddecreaseinbothcorticalfailureandtrabecularfailureloads.Thisresearchshouldbehelpfultotheclinicalassessmentoffemurfractureriskduetoage-relatedboneloss.