简介: [摘要 ] 目的 探讨美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎的疗效及其对炎性因子的影响。 方法 选取 2018年 1月~ 2020年 1月我院收治的溃疡性结肠炎患者 80例,随机分为两组,每组各 40例,两组患者均予常规对症治疗,同时两组均予美沙拉嗪缓释颗粒,观察组同时加用双歧三联活菌胶囊,治疗后比较两组患者治疗后的临床疗效,以及两组患者治疗前后 TNF-α、 IL-10水平的变化情况及两组患者治疗前后的临床症状积分变化情况。结果 观察组治疗后的总有效率为 95.00%,显著高于对照组的总有效率 70.00%,两组疗效比较差异具有显著性( P<0.05)。治疗后,两组患者的炎性因子 TNF-α、 IL-10水平较治疗前显著降低( P<0.05)。且观察组患者治疗后的 TNF-α、 IL-10水平显著低于对照组( P<0.05)。观察组患者治疗后的临床症状积分为( 2.56±0.85)分,与治疗前及对照组比较,差异有统计学意义( P<0.05)。 结论 美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎疗效确切,且可以抑制炎症反应,值得临床推广和应用。 [关键词 ] 溃疡性结肠炎 ;美沙拉嗪 ;双歧三联活菌 ;炎性因子 [Abstract] Objective To investigate the efficacy of mesalazine combined with Bifid Triple Viable Bacteria in the treatment of ulcerative colitis and its influence on inflammatory factors. method Methods: 80 patients with ulcerative colitis in our hospital from January 2018 to January 2020 were selected and randomly divided into two groups, 40 cases in each group. Both groups were given conventional symptomatic treatment, while the two groups were given mesalazine sustained-release granules. The observation group was also given Bifid Triple Viable capsules. After treatment, the clinical efficacy of the two groups of patients after treatment, as well as TNF - α, IL-10 water before and after treatment, were compared between the two groups The changes of the two groups of patients before and after treatment of clinical symptoms integral changes. Results the total effective rate of the observation group was 95.00%, which was significantly higher than that of the control group (70.00%). There was a significant difference between the two groups (P < 0.05). After treatment, the levels of inflammatory factors TNF - α and IL-10 in the two groups were significantly lower than those before treatment (P < 0.05). The levels of TNF - α and IL-10 in the observation group were significantly lower than those in the control group (P < 0.05). The clinical symptom score of the observation group after treatment was (2.56 ± 0.85), and the difference was statistically significant (P < 0.05). Conclusion mesalazine combined with Bifid Triple Viable Bacteria is effective in the treatment of ulcerative colitis, and can inhibit inflammatory reaction, which is worthy of clinical promotion and application.
简介:摘要:目的: 分析慢性溃疡性直肠炎患者护理干预效果。方法:本次研究选择 2015 年 7 月 ~2017 年 7 月来我院接受治疗的慢性溃疡性直肠炎患者 80 例为研究对象,根据护理方法将其分为对照组 40 例、观察组 40 例,分别比较两组护理效 果。结果:比较两组患者临床干预效果, 对照组有效率为 65.00% ;观察组有效率为 95.00% ,数据比较差异显著,具有统计学意义。 观察组护理效果显著优于对照组,组间差异显著,具有统计学意义。结论:将优质护理应用到慢性溃疡性直肠炎患者中,有利于患者护理效果与满意度的提升。
简介:【摘要】目的 分析骨质疏松性腰椎压缩性骨折用针灸结合中药外敷治疗的效果。方法 选取2020年1月-2022年1月该院收治的82例骨质疏松性腰椎压缩性骨折患者,利用随机数字表法,分为参照组,41例,用常规治疗,观察组,41例,用针灸结合中药外敷治疗。比较两组疗效。结果 观察组治疗后的VAS评分低于参照组;观察组的不良情况发生率少于参照组,有统计学意义(P