简介:Objectives:Toevaluateoutcomesintreatingcarcinomaofexternalauditorycanal(EAC)andtoanalysisfactorswhicheffecttheprognosisofthisdisease.Methods:Aretrospectivelyreviewof16patientstreatedforcarcinomaofEACatourdepartmentbetweenApril2000andApril2014wasconducted.Allpatientsunderwentsurgicaltreatmentandthediagnosisconfirmedbypathologicalexamination.Results:Therewereadenoidcysticcarcinoma(ACC)in8patients,squamouscellcarcinoma(SCC)in5patients,adenocarcinoma(AC)in2patients,andverrucouscarcinoma(VC)in1patient.ThetumorswereclassifiedasStageIin4cases,StageIIin2cases,StageIIIin3cases,andStageⅣin7cases.Fivepatientsunderwentextensivetumorresection(ETR),2patientsunderwentlateraltemporalboneresection(LTBR),5patientsunderwentmodifiedLTBR,2patientsunderwentsubtotaltemporalboneresection(STBR),and2patientsunderwentonlyopenbiopsy.Besides,adjunctiveprocedures,includingneckdissection,parotidectomyandpinnaresectionwereperformedwhenindicated.Tenpatientsreceivedpostoperativeradiotherapy.Bytheendoffollowup,twopatientshaddiedoftheirdisease,2losttofollowup,2survivedwiththedisease,andtherestsurviveddisease-free.Themedianfollow-upperiodwas24months.Conclusion:CompletetumorresectionappearstobeaneffectivetreatmentforcarcinomaoftheEAC.PatientswithSCCseemtohaveworseprognosisthanthosewithACC.Radiationtherapyseemslesseffectiveforihediseasethansurgicaltreatment.
简介:Asanresearchexampleofthewidelyexistingcooperation-competitionsystems,theauthorspresentanempiricalinvestigationonafruitnutritivefactornetwork.Itisdescribedbyanode-weightedbipartitegraph.Thefruitnutritivefactorsaredefinedasthenodes,andtwonodesareconnectedbyanedgeifatleastonefruitcontainsthesetwonutritivefactors.Thefruitsaredefinedasthecollaborationacts.Thenode-weightW_(nt),whichsignifiesthe'importancedegree'ofeachactornode,isdefinedasthecontentofanutritivefactorinafruit.Theempiricalinvestigationresultsshowsomeuniquefeatures.Thenode-weightdistributionstakeso-called'shiftedpowerlaw'functionforms,buttheact-weightdistributiontakesanormalform.Thedegreeandact-degreedistributionsshowimpulsive-spectrumlikeforms.Theseobservationsmaybehelpfulforthestudyoffruits.Thenetworkdescriptionmethodproposedinthisarticlemaybeuniversalforakindofcooperation-competitionsystems.
简介:客观:为了调查与外部fixator在处理期间测量主要axials火车的不同方法并且发现,合适的压缩在一个早阶段由外部fixator装载了。方法:十八只健康大耳朵的兔子随机根据不同测量方法被划分成二个组:组织A和组B。在组A,一个紧张计量器与502胶水在外部胫骨的外皮被加,并且在组B,一个骨头cement-coatedstrain计量器在内部胫骨的外皮上被安装。组A和B被划分成二亚群A1,A2和B1,B2,分别地根据一半并且与身体重量一样的压力。Z塑造左中间柄的胫骨的截骨术被externalfixator执行并且修理。结果:组A的sealer曲线在早阶段期间戏剧性地变化了。当后者紧张价值比前者高时,内部、外部的外皮的Thetrendlines在到达稳定的阶段以后一致地去了。到达最稳定的年龄的组B的时间是短的,但是它的绝对紧张价值是不到组A的。在他们被贴在稳定的阶段以前,当亚群B1和B2的结果是一样的时,亚群A1的拒绝的速度比SubgroupA2的慢慢地是更多。在它衰退了以后,当时,组A有一个上升趋势组Bdidn“t。在他们到达了稳定的阶段,两亚群A1和A2had以后一个衰退趋势当亚群A2比亚群A1快速是更多时,当亚群B2波动时,亚群B1在明确的水平被保留。结论:在外部fixatorcan下面的轴的紧张被骨头水泥测量在vivo的涂紧张的计量器。数据可以建议身体重量负担的那一半对外部fixator合适。
简介:Anewretrofittingmethodisproposedhereinforreinforcedconcrete(RC)structuresthroughattachmentofanexternalstructure.Theexternalstructureconsistsofafiberconcreteencasedsteelframe,connectionslabandtransversebeams.Theexternalstructureisconnectedtotheexistingstructurethroughaconnectionslabandtransversebeams.Pseudostaticexperimentswerecarriedoutononeunretrofittedspecimenandthreeretrofittedframespecimens.Thecharacteristics,includingfailuremode,crackpattern,hysteresisloopsbehavior,relationshipofstrainanddisplacementoftheconcreteslab,aredemonstrated.Theresultsshowthattheloadcarryingcapacityisobviouslyincreased,andtheextensionlengthoftheslabandthenumberofcolumnswithintheexternalframeareimportantinfluencefactorsontheworkingperformanceoftheexistingstructure.Inaddition,thedisplacementdifferencebetweentheexistingstructureandtheouterstructurewascausedmainlybythreefactors:sheardeformationoftheslab,extractionoftransversebeams,anddriftoftheconjunctionpartbetweentheslabandtheexistingframe.Furthermore,thetotaldeformationdeterminedbythefirsttwofactorsaccountedforapproximately80%ofthedamage,thereforethesefactorsshouldbecarefullyconsideredinengineeringpracticetoenhancetheeffectsofthisnewretrofittingmethod.
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简介:Itisstandardpractice,wheneveraresearcherfindsanewgene,tosearchdatabasesforgenesthathaveasimilarsequence.Itisnotstandardpractice,wheneveraresearcherfindsanewgene,tosearchforgenesthathavesimilarexpression(coexpression).Failuretoperformco-expressionsearcheshasleadtoincorrectconclusionsaboutthelikelyfunctionofnewgenes,andhasleadtowastedlaboratoryattemptstoconfirmfunctionsincorrectlypredicted.WepresentheretheexampleofGliaMaturationFactorgamma(GMF-gamma).Despiteitsname,ithasnotbeenshowntoparticipateingliamaturation.ItisageneofunknownfunctionthatissimilarinsequencetoGMF-beta.ThesequencehomologyandchromosomallocationledtoanunsuccessfulsearchforGMF-gammamutationsinglioma.WeexaminedGMF-gammaexpressionin1432humancDNAlibraries.Highestexpressionoccursinphagocytic,antigen-presentingandotherhematopoieticcells.WefoundGMF-gammamRNAinalmosteverytissueexamined,withexpressioninnervoustissuenohigherthaninanyothertissue.OurevidenceindicatesthatGMF-gammaparticipatesinphagocytosisinantigenpresentingcells.Searchesforgeneswithsimilarsequencesshouldbesupplementedwithsearchesforgeneswithsimilarexpressiontoavoidincorrectpredictions.