简介:TheapplicationofXzeoliteintheareasforproducingpara-xylenebyadsorptiveseparation,N2/O2separation,etc.,wasreviewed,andtheframeworkSiO2/Al2O3molarratio,thecationsandthewatercontentofXzeolitesignificantlyaffecteditsselectivityandcapacity.Astheactivecomponentofpara-xyleneadsorbent,theXzeolitewithaframeworkSiO2/Al2O3molarratioof2.2-2.4coupledwithcationsofBa^2+andK^+,aswellasawatercontentof4.0%-5.0%exhibitedhigherpara-xyleneselectivity.ForN2/O2separation,higherN2capacityandN2/O2separationfactorwereachievedwhentheXzeolitehadaframeworkSiO2/Al2O3molarratioof2.0coupledwithLi^+cations.TheintroductionofanothercationinXzeolitecouldfurtherincreasetheN2/O2separationfactor,whiletheadsorptionofwater,however,couldleadtoaremarkabledecreaseofN2capacity.Besides,theXzeolitecouldbeusedinadsorptiveseparationofhighlypureHeandselectiveadsorptionofCO2,CO,CH4,N2,Ar,andH2.
简介:Next-generationsequencing(NGS)isanewtechnologyusedforDNAandRNAsequencingandvariant/mutationdetection.NGScansequencehundredsandthousandsofgenesorwholegenomeinashortperiodoftime.Thesequencevariants/mutationsdetectedbyNGShavebeenwidelyusedfordiseasediagnosis,prognosis,therapeuticdecision,andfollowupofpatients.Thecapacityofitsmassiveparallelsequencingoffersnewopportunitiesforpersonalizedprecisionmedicine.
简介:Inmarineengineering,thestrengthofasubmarinesedimentisanindispensableparameterforassessmentofconstruction.Inthisstudy,afree-fallconepenetratornamedIPenwasdevelopedtorealizearapidandefficientmeasurementofsedimentstrength.Theequipmentischaracterizedbymodulardesignandself-containeddataacquisition.Itisequippedwithanaccelerationsensor,awaterpressuresensor,andapiezoconepenetrationtest(CPTu)probe.Itisdesignedtobereleasedfromnearseabedsurfacewithareleaserandthenfallfreelytoprovideahigherpenetrationvelocity.Itsmaximumworkingdepthisapproximately2500mandmaximumpenetrationdepthisapproximately3m.Toderivethecorrelationbetweenpenetrationresistanceandsedimentstrength,acalibratorwasdevisedtodeterminethepenetration-ratefactor.Inaddition,thefactorapplicabletoinsitutestpointswasdeterminedinlaboratoryexperiments.InJune2016,theIPenwastestedinsituintheSouthYellowSea,China,duringasharedvoyagefundedbytheNationalScienceFoundation.Meanwhile,undisturbedcolumnsampleswerecollectedforlaboratorytests.Basedontheinsitutestresults,itwasdemonstratedthattheIPencouldaccuratelyrecordtheworkingstatesofvarioussensorsduringthefreelyfallingcourse.IPentestresultsreliablyreflectedthesedimentstrengthatallthetestingpointswhencomparedwithlaboratorycalibrationtests,insituvanetestsandpenetrationtests,laboratorypenetrationtests,andunconsolidatedandundrainedtriaxialcompressiontests.
简介:Aneuralnetwork(NN)isapowerfultoolforapproximatingboundedcontinuousfunctionsinmachinelearning.TheNNprovidesaframeworkfornumericallysolvingordinarydifferentialequations(ODEs)andpartialdifferentialequations(PDEs)combinedwiththeautomaticdifferentiation(AD)technique.Inthiswork,weexploretheuseofNNforthefunctionapproximationandproposeauniversalsolverforODEsandPDEs.ThesolveristestedforinitialvalueproblemsandboundaryvalueproblemsofODEs,andtheresultsexhibithighaccuracyfornotonlytheunknownfunctionsbutalsotheirderivatives.ThesamestrategycanbeusedtoconstructaPDEsolverbasedoncollocationpointsinsteadofamesh,whichistestedwiththeBurgersequationandtheheatequation(i.e.,theLaplaceequation).
简介:Theradiancesscatteredoremittedbycloudsdemonstratediversefeaturesatdifferentwavelengthsduetodifferentcloudphysicalstructures.Thispaperpresentsamethod(thesmallest-radiance-distancemethod,SRaDM)ofrevealingthephysicalstructuresofclouds.Themethodisbasedonmulti-spectralradiancesmeasuredbytheModerateResolutionImagingSpectroradiometer(MODIS)onboardAqua.TheprincipleandmethodologyofSRaDMisdeducedandprovidedinthispaper.CorrelationanalysisbasedondatafromMODISandCloudProfilingRadar(onboardCloudSat),collectedfromJanuary2007toDecember2010overanoceanarea(15°N–45°N,145°E–165°E),ledtoselectionofradiancesat13wavebandsofMODISthatdemonstratedhighsensitivitytocloudphysicalstructures;radiancesattheselectedwavebandsweresubjectedtoSRaDM.TheStandardizedEuclideandistanceisintroducedtoquantifythedegreeofchangesinmulti-spectralradiances(termedDrd)andinphysicalstructures(termedDst)betweencloudprofiles.StatisticsbasedonnumerouscloudprofilesshowthatDrddecreasesmonotonicallywithadecreaseinDst,whichimpliesthatsmallDrdalwaysaccompaniessmallDst.AccordingtothelawofDrdandDst,thenewmethod,SRaDM,forrevealingphysicalstructuresofcloudsfromthecollocationofcloudprofilesofsimilarmulti-spectralradiances,ispresented.Then,twosuccessfulexperimentsarepresentedinwhichcloudphysicalstructuresarecapturedusingmulti-spectralradiances.SRaDMprovidesawaytoobtainknowledgeofthephysicalstructuresofcloudsoverrelativelylargerareas,andisanewapproachtoobtaining3Dcloudfields.
简介:Basedontheprincipleformulaforthefour-componentstrainmeters,wecandirectlyobtainthespecificplanestrain,shearstrainandazimuthalangleoftheprincipalstrain,andthemaximumandminimumprincipalstrainscalculatedafterwardsaretheindirectresult.TheproblemsofpracticalityofthesensitivitycoefficientsAandBofplanestrainandshearstrainarethendiscussed.Basedonthisidea,weanalyzedtheobservationdataofseveralfourcomponentboreholestrainmetersneartheepicenteroftheYiliangMS5.7earthquakein2012andtheLudianMS6.5earthquakein2014intheZhaotongarea,YunnanProvince.Theresultsshowthattheanalysisbasedontheperspectiveofplanestrainandshearstrainhasanobviouslybettereffectthanthatbasedonthecomponentreadings,andcandirectlypeelofftherespectiveabnormalityoftheplanestrainandshearstrain.Inaddition,thecorrelationcoefficientcurvesbetweenmeasureddataoftwoplanestrainsshowsignificantanomalieswhichoftenoccurseveraldaysbeforeandduringtheearthquake.
简介:Cable-membranestructureshavesmallrigidityandarehighlysensitivetowind.Structuralhealthmonitoringisnecessarytoensuretheserviceabilityandsafetyofthestructure.Inthisresearch,thedesignmethodofastructuralhealthmonitoringsystemisusingthecharacteristicsofacable-membranestructure.TakingtheYueyangSanheAirportTerminalasanexample,afiniteelementmodelisestablishedtodeterminethecriticalstructuralcomponents.Next,theengineeringrequirementsandtheframeworkofthemonitoringsystemarestudiedbasedontheresultsofnumericalanalysis.Thespecificimplementationofthestructuralhealthmonitoringisthencarriedout,whichincludessensorselection,installationandwiring.TheproposedframeworkissuccessfullyappliedtothemonitoringsystemfortheYueyangAirportterminalbuilding,andthesynchronousacquisitionoffiberBragggratingandaccelerationsensorsignalsisimplementedinaninnovativeway.Thesuccessfulimplementationandoperationofstructuralhealthmonitoringwillhelptoguaranteethesafetyofthecablemembranestructureduringitsservicelife.
简介:Aunanoparticles(AuNPs)wereelectrodepositedatthehighlyorderedanataseTiO2nanotubearray(TiO2NA)electrodeundersonicating,andtheAuNP-TiO2NAsensorwascharacterizedbyscanningelectronmicroscope(SEM),X-rayphotoelectronspectroscopy(XPS),X-raydiffraction(XRD).ThephotoelectrochemicalexperimentsindicatetheAuNP-TiO2NAsensorhaslowerphotoelectro-resistance,higherphotoelectrocatalyticalactivityandstabilitythanthatofpureTiO2NAsensorunderthesameconditions.Theas-preparedsensorcanbeusedforthedeterminationofchemicaloxygendemand(COD)inrealsamples,andtheobtainedresultsarecomparablewellwiththoseofbystandardK2Cr2O7method.Themethodproposedissimple,fast,costeffective,andenvironmentallyfriendly.
简介:Next-generationsequencing(NGS)technologyiscapableofsequencingmillionsorbillionsofDNAmoleculessimultaneously.Therefore,itrepresentsapromisingtoolfortheanalysisofmoleculartargetsfortheinitialdiagnosisofdisease,monitoringofdiseaseprogression,andidentifyingthemechanismofdrugresistance.OnbehalfoftheTumorBiomarkerCommitteeoftheChineseSocietyofClinicalOncology(CSCO)andtheChinaActionableGenomeConsortium(CAGC),thepresentexpertgroupherebyproposesadvisoryguidelinesonclinicalapplicationsofNGStechnologyfortheanalysisofcancerdrivergenesforprecisioncancertherapy.Thisgroupcomprisesanassemblyoflaboratorycancergeneticists,clinicaloncologists,bioinformaticians,pathologists,andotherprofessionals.Aftermultipleroundsofdiscussionsandrevisions,theexpertgrouphasreachedapreliminaryconsensusontheneedofNGSinclinicaldiagnosis,itsregulation,andcompliancestandardsinclinicalsamplecollection.Moreover,ithaspreparedNGScriteria,thesequencingstandardoperationprocedure(SOP),dataanalysis,report,andNGSplatformcertificationandvalidation.
简介:Thepulsed-sprayfluid-bedgranulation(PSFBG)processwasinvestigatedandoptimizedusingdefinitivescreeningdesign,arecentlyproposednewclassofthree-leveldesignofexperimentmethod.Suchadesignenabledquadraticmodelstobeestablishedthatdescribedtheeffectofsixinputprocessparameters-inletairtemperature,inletairhumidity,bindersprayrate,atomizationpressure,pulseperiod,andpulsewidth-onthegranulequalityinaPSFBGprocess.Mathematicalmodelsofthemeanparticlesize,relativesizedistributionwidth,productionyield,andporosityweredevelopedtoquantifytherelationshipsbetweentheinfluencingfactorsandcriticalqualityattributes.Onthebasisofconstraintsonthedesiredgranuleproperties,adesignspaceforPSFBGwasdeterminedandrangesoftheoperatingparametersweredefined.Anacceptabledegreeofpredictionwasconfirmedbyvalidationexperiments,demonstratingthereliabilityandeffectivenessofusingdefinitivescreeningdesigntostudythePSFBGprocess.Thismethodcanacceleratescreeningandoptimizationofthisprocesswithinalargemultidimensionaldesignspace.