简介：Strokeisaleadingcauseoflong-termdisability.Moststrokepatientsregaintheirfunctionpartiallyorfullyduringthefirst3–6monthsdependingonlocationandsizeofthelesion.Duringthisfunctionalrecoveryphase,corticalreorganizationorplasticityoccurs,andphysiologicalresponsivenessorneuronalexcitabilityisalteredintheipsilesionalandcontralesionalareas.However,howtodrivesuccessfulplasticchangesorsuccessfulstrokerecoveryarenotfullyelucidatedyet.

简介：Strokeisaleadingcauseofdeathanddisabilityinadultsworldwide.Fordecades,theprimaryapproachandgoaloftherapyforstrokehasfocusedonneuroprotection,namelytreatingtheinjuredtissue,withinterventionsdesignedtoreducethevolumeofcerebralinfarction.Enormouseffortinthelaboratoryhasbeendevotedtothedevelopmentof

简介：加中国药用的忿恨评估针灸的治疗学的功效并且在在击以后的半身麻痹对待影响手足的浮肿洗。

简介：Oxidativestressiscloselyassociatedwithsecondarycelldeathinmanydisordersofthecentralnervoussystemincludingstroke,Parkinson’sdisease,Alzheimer’sdisease.Amongmanyaberrantoxidativestress-associatedproteins,DJ-1hasbeenassociatedwiththeoxidativestresscelldeathcascadeprimarilyinParkinson’sdisease.Althoughprincipallyexpressedinthecytoplasmandnucleus,DJ-1canbesecretedintotheserumunderpathologicalcondition.Recently,aclosepathologicalassociationbetweenDJ-1andoxidativestressinstrokehasbeenimplicated.Tothisend,weandothershavedemonstratedtheimportantroleofmitochondriainneuroprotectionforstrokebydemonstratingthatthetranslocationofDJ-1inthemitochondriacouldpotentiallymitigatemitochondrialinjury.Here,wediscussourrecentfindingstestingthehypothesisthatDJ-1notonlyfunctionsasaformofintracellularprotectionfromoxidativestress,butthatitalsoutilizesparacrineand/orautocrinecuesinordertoaccomplishextracellularsignalingbetweenneighboringneuronalcells,resultinginneuroprotection.ThisarticlehighlightsrecentevidencesupportingthestatusofDJ-1askeyanti-oxidativestresstherapeutictargetforstroke.

简介：在对待击以后的便秘加专利汉语药观察针灸的临床的功效。

简介：观察平衡在治疗以后在击以后的上面的手足spasticity和electromyography(EMG)的变化上刺破操作的yin-yang的效果。

简介：BackgroundTheclinicalcharacteristicsofstrokepatientstreatedwithdoubleanti-platelettherapy(DAPT)afterpercutaneouscoronaryintervention(PCI)isnotclear.MethodsIntotal,2675patientsunderwentPCIandDAPTinGuangdongGeneralHospital,and68outofthemwerehospitalizedduetosuspectedstroke,ofwhom23werediagnosedashavingstroke.Dataofthe23strokepatientswerecollectedandtraditionalriskfactorsassociatedwithstrokewereanalyzedretrospectively.ResultsThemeanageofthesepatientswas75.6±8.7years,and20(87.0%)weremales.Notably,19patientswerecomplicatedwithhypertension,7withdiabetesmellitus,7withprevioushistoryofstroke,nonewithatrialfibrillation(AF)orpatentforamenovale(PFO).Specifically,22patientswerediagnosedwithischemicstroke,and1patientwithhemorrhagicstroke.ConclusionStrokeinpatientstreatedwithDAPTafterPCIwascorrelatedwithadvancedage,gender,hypertension,diabetesmellitus,strokehistory.Longtermelectrocardiography(ECG)maybeneededforthediagnosisofAF,whiletrans-esophagealechocardiography(TEE)maybeneededforPFO.

简介：为了观察由在yin和yang顶点上呼吸增强并且减少操作的效果，与ischemic击在病人为膝关节的马达功能指。

简介：Moststudiesaddressingthespecificityofmeridiansandacupuncturepointshavefocusedmainlyonthedifferentneuraleffectsofacupunctureatdifferentpointsinhealthyindividuals.Thisstudyexaminedtheeffectsofacupunctureonbrainfunctioninapathologicalcontext.Sixteenpatientswithischemicstrokewererandomlyassignedtotruepointgroup(trueacupunctureatrightWaiguan(SJ5))andshampointgroup(shamacupuncture).Resultsoffunctionalmagneticresonanceimagingrevealedactivationinrightparietallobe(Brodmannareas7and19),therighttemporallobe(Brodmannarea39),therightlimbiclobe(Brodmannarea23)andbilateraloccipitallobes(Brodmannarea18).Furthermore,inhibitionofbilateralfrontallobes(Brodmannarea4,6,and45),rightparietallobe(Brodmannareas1and5)andlefttemporallobe(Brodmannarea21)wereobservedinthetruepointgroup.Activationintheprecuneusofrightparietallobe(Brodmannarea7)andinhibitionoftheleftsuperiorfrontalgyrus(Brodmannarea10)wasobservedintheshamgroup.Comparedwithshamacupuncture,acupunctureatWaiguaninstrokepatientsinhibitedBrodmannarea5onthehealthyside.Resultsindicatedthatthealteredspecificityofsensation-associatedcortex(Brodmannarea5)ispossiblyassociatedwithacentralmechanismofacupunctureatWaiguanforstrokepatients.

简介：Basementmembranedegradationandblood-brainbarrierdamageappearaftercerebralinfarction,severelyimpactingneuronalandbrainfunctioning;however,theunderlyingpathogeneticmechanismsremainpoorlyunderstood.Inthisstudy,weinducedcerebralinfarctioninstrokepronespontaneouslyhypertensiveratsbyintragastricadministrationofhigh-sodiumwater(1.3%NaCl)for7consecutiveweeks.Immunohistochemicalandimmunofluorescenceassaysdemonstratedthat,comparedwiththenon-infarctedcontralateralhemisphere,stroke-pronespontaneouslyhypertensiveratsonnormalsodiumintakeandWistar-Kyotorats,matrixmetalloproteinase-9expression,thenumberofbloodvesselswithdiscontinuouscollagenIVexpressionandmicrovesseldensityweresignificantlyhigher,andthenumberofcontinuouscollagenIV-positivebloodvesselswaslowerintheinfarctborderzonesofstroke-pronespontaneouslyhypertensiveratsgivenhigh-sodiumwater.Linearcorrelationanalysisshowedmatrixmetalloproteinase-9expressionwaspositivelycorrelatedwiththenumberofdiscontinuouslycollagenIV-labeledbloodvesselsandmicrovesseldensityincerebralinfarctsofstroke-pronespontaneouslyhypertensiverats.Theseresultssuggestthatmatrixmetalloproteinase-9upregulationisassociatedwithincreasedregionalangiogenesisanddegradationofcollagenIV,themajorcomponentofthebasallamina,instroke-pronespontaneouslyhypertensiveratswithhigh-sodiumwater-inducedfocalcerebralinfarction.