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简介：Theauthorsfocusedtheirattentionontheestablishmentofamesenchymalstemcell(MSC)modelforscreeningtraditionalChinesemedicines(TCMs)soastoinvestigatetheeffectsofShuanglongFormula(SLF)components(Ginsenosidesandsalvianolicacids)andingredients(ginsenosideRb1andsalvianolicacidB)oncardiomyocytedifferentiationfromMSCs.TheSLFcomponentswereanalyzedandquantifiedbyHPLC-TOF-MS.CardiomyocytedifferentiationwasinducedbyculturingMSCsintheinductionmediumsupplementedwithSLFingredients,SLFcomponents,5-azacytidine(5-aza),5-aza+SLFingredientsand5-aza+SLFcomponents,respectively,forupto30d,andevulatedbytheexpressionofCardiac-specificmyosinheavychain(MHC)andtroponinI(TnI)viaimmunofluoresentstaining.Slowgrowthrateandchangedmorphologywereobservedduringcardiomyocytedifferentiation.After20dofinduction,differentiatingMSCswerepositiveforMHCandTnIstaining.TheeffectsofSLFcomponentswerebetterthanthoseofSLFingredients.Takentogether,SLFcaninducethedifferentiationofMSCsintocardiomyogeniccellsinvitro,andMSCscanbeusedasapowerfultoolforscreeningTCMs.

简介：Poly(lactide-co-glycolide)-poly(ethylene乙二醇)-poly(lactide-co-glycolide)(PLGA-PEG-PLGA)triblock共聚物是作为macroinitiator和亚锡的octoate与木钉通过LA和GA的戒指洞聚合被综合催化剂。进在水的答案的微粒自我装配的amphiphilic共聚物，和形成的hydrogels作为在相对高的集中的温度的增加(>15wt%)。hydrogel的有利degradability被证实由在vitro并且在vivo降级实验。好细胞并且thermogel的tissular相容性被表明。骨头髓的优秀粘附和增长间充质的干细胞为软骨织物工程赋予了PLGA-PEG-PLGAthermogellinghydrogel以迷人的前景。

简介：Sweetsorghum,theworld'sfifthmostimportantcerealafterrice,corn,wheatandbarley,isaveryattractivesourceforbiomassproduction.Thisrawmaterialcomplementssugarcaneproductionandisemergingastheidealfeedforanimalsandfortheproductionofthefirst-generationofbiofuels,suchasethanolandvalue-addedchemicals.Atpresent,mostofthestudiesaboutsweetsorghumfocusonutilization(suchasethanolproduction),andthestudyofsugeraccumulationinstemarerarely.