BackgroundAcuteinferiorandanteriormyocardialinfarctionoftenleadstorightventricular(RV)functiondecrease.EstimationofRVfunctionischallengingduetothecomplexRVgeometry.Fewstudieshavebeenconductedtoinvestiogatetheeffectsofacutemyocardialinfarction(AMI)onrightventricularfunctions(RVFs).Two-dimensionSpeckleTrackingImaging(STI)isanovelmethodthatallowsforasegmentbasedmeasurementofmyocardialdeformationandmayhavethepotentialtoquantifyRVdysfunctionmorepreciselythantheconventionalparametersofRVfunction.Therefore,inthisstudyweanalyzedtheRVfunctioninAMIpatientsbyusingthisnoveltechnique.MethodsThirty-fourpatientswithacuteinferiormyocardialinfarction(AIMI),31patientswithacuteanteriormyocardialinfarction(AAMIand30agematchedhealthyinpidualswereenrolledforthestudy.2Dspeckletrackingimaging(STI)wasusedtoobtain2Dimagingattheapicalfour-chamberviewunderrestcondition.Peaksystolicstrainsandstrainratesofallsegmentsinrightventricularfreewallwereanalyzed.ResultsComparedtothenormalcontrolgroup,longitudinalpeaksystolicstrain(ε),strainrate(SRs),earlydiastolicstrainrate(SRe)andlatediastolicstrainrate(SRa)inallsegmentsofrightventricularfreewallweresignificantlylowerinAMIpatients.ε,SRs,SReandSRaofeachsegmentofRVintheAIMIgroupweredecreasedsignificantlythanthoseofthenormalcontrolgroup(P<0.05).ε,SRs,SReandSRaofeachsegmentofRVintheAAMIgroupwerelowerthantheseinthecontrolgroup.ExceptforbasalsegmentalSRa,thereweresignificantdifferencesamongotherparameters(P<0.05).ConclusionsRVFsareimpairedinAMIpatients.RVFscouldbeaccuratelyandsensitivelyassessedwithSTI.