UsingaregionalclimatemodelMM5nestedtoanatmosphericglobalclimatemodelCCM3,aseriesofsimulationsandsensitivityexperimentshavebeenperformedtoinvestigatetherelativeLastGlacialMaximum(LGM)climateresponsetodifferentmechanismsoverChina.Modelsimulationsofthepresentday(PD)climateandtheLGMclimatechangeareingoodagreementwiththeobservationdataandgeologicalrecords,especiallyinthesimulationofprecipitationchange.UnderthePDandLGMclimate,changesofearthorbitalparametershaveasmallinfluenceontheannualmeantemperatureoverChina.However,themagnitudeoftheeffectshowsaseasonalpattern,withasignificantresponseinwinter.Thus,thisinfluencecannotbeneglected.DuringtheLGM,CO_2concentrationreacheditslowestpointto200ppmv.ThisresultsinatemperaturedecreaseoverChina.TheinfluencesofCO_2concentrationonclimateshowseasonalandregionalpatternsaswell,withasignificantinfluenceinwinter.Onthecontrary,CO_2concentrationhaslessimpactinsummerseason.Insomecases,temperatureevenincreaseswithdecreasinginCO_2concentration.Thistemperatureincreaseistheoutcomeofdecreaseincloudamount;henceincreasethesolarradiationthatreachedtheearth'ssurface.Thisresultsuggeststhatcloudamountplaysaveryimportantroleinclimatechangeandcoulddirecttheresponsepatternsofsomeclimatevariablessuchastemperatureduringcertainperiodsandovercertainregions.IntheTibetanPlateau,thetemperatureresponsestochangesoftheabovetwofactorsaregenerallyweakerthanthoseinotherregionsbecausethecloudamountinthisareaisgenerallymorethanintheotherareas.Relativetothecurrentclimate,changesinorbitalparametershavelessimpactontheLGMclimatethanchangesinCO_2concentration.However,bothfactorshaveratherlesscontributionstotheclimatechangeintheLGM.About3%-10%changesintheannualmeantemperaturearecontributedbyCO_2.