简介：上接2018年第2期第75页（5）眼表炎症评分眼红是门诊常见病,多数由干眼引起。设备可自动分析球结膜及睫状充血并分级。标准化、量化的结膜和睫状体充血等级分析,便于用药疗效观察和治疗隨访。总之,眼表综合分析可进行非侵入式泪膜破裂时间、泪河高度测量,以及睑板腺拍摄脂质层观察。2.眼表综合分析仪检查方法眼表综合分析仪主要由一个Placido盘、一个操纵杆及一台安装有Phoenix软件的电脑所组成。

简介：随着视网膜脱离手术的迅速发展和治愈率的不断提高，其对眼表健康的负面影响也越来越受到学者们的重视。我们就各类视网膜脱离手术对眼表健康的负面影响作一综述，以期为视网膜脱离手术术式的改进提供参考。

简介：目的：分析《标准对数视力表》与《低视力视力表》对远用视力检查的临床意义及临床价值。方法：随机抽取本院验光部验光患者59例（118眼）,每位患者分别进行两种视力表的远用视力检查,然后记录裸眼视力以及矫正视力检查结果,再进行配对设计资料检验。结果：裸眼视力检查t=2.9944,矫正视力检查t=3.5564,P〈0.05,两种视力表无论是裸眼视力还是矫正视力在统计学上均有显著性差异。结论：两种视力表的视力检查结果有所差异,裸眼视力相差19.953′视角,矫正视力相差15.849′视角,且低视力专用视力表的均值均小于标准对数视力表。

简介：干眼症是十分常见的眼表疾病,其发病机制至今尚未明确.近年来的研究表明基于免疫的炎症反应可能是各种类型干眼症发病的共同机制.泪腺及眼表面的炎症可导致泪腺及眼表上皮细胞损伤及凋亡、泪液中水样液及黏液的分泌减少,而性激素水平的异常可能是导致此炎症反应发生的重要因素,本文复习了以上热点问题的相关文献作一综述.

简介：我们归纳、分析、整理近年来的文献资料，简述2型糖尿病患者眼表改变的临床特点，为临床诊断和治疗糖尿病性眼表病变提供理论上的依据。

简介：目的通过眼表观察比较两种翼状胬肉手术的临床效果。方法选取76例原发翼状胬肉患者随机分成AB2组,各38人。A组采取翼状胬肉切除联合术中使用丝裂霉素C;B组采取翼状胬肉切除联合带自体角膜缘干细胞的结膜移植。比较2组患者的泪膜破裂时间（BUT）,复发率,角膜修复时间、形态,术后不适症状的改善。结果2组患者角膜修复行为不同。2组患者于术后一周观察角膜上皮修复程度,B组好于A组（P〈0.05）;2组患者BUT比较,A组术前与术后无显著性差异（P〉0.05）;B组术前与术后有显著性差异（P〈0.05）;A、B两组术后6个月泪膜破裂时间,B组较A组更长（P〈0.05）;2组术后6个月眼部干涩、异物感等症状改善比较无显著性差异（P〉0.05）;术后6个月复发率比较无显著性差异（P〉0.05）。结论翼状胬肉切除联合自体带角膜缘干细胞的结膜移植术后角膜上皮修复快,泪膜稳定性有明显提高。

简介：目的观察在翼状胬肉术中采取干预措施对术后眼表修复的影响。方法临床病例对照研究。通过对82例（88只眼）患者进行随机分组。对照组常规进行翼状胬肉切除＋角膜缘干细胞移植术;干预组在常规翼状胬肉切除＋角膜缘干细胞移植术中采取小牛血去蛋白眼用凝胶全程覆盖角膜、20%乙醇棉签辅助角膜上皮残存胬肉组织清除、手术区域结膜组织整复等干预措施。观察两组患者术后眼表组织修复情况及主观感受。结果干预组患者术后自觉刺激症状较对照组明显减轻,裂隙灯显微镜检查见干预组眼表组织愈合情况明显优于对照组。术后远期疗效两组无明显差异。结论翼状胬肉术中采用干预措施,加强眼表组织保护,有利于早期眼表组织修复,改善患者术后早期不适症状。

简介：目的观察自制全结膜囊羊膜固定器在重症眼表烧伤行羊膜遮盖手术中应用效果。方法在11例（13眼）眼部重症烫伤患者治疗中采用自制全结膜囊羊膜固定器将羊膜固定于眼表及眼睑皮肤面。根据病情需要更换羊膜，随访3月至3年。结果患者平均手术时间为（8．0±3．0）分钟；眼表组织上皮化时间（13．2±11．3）天。重复手术次数3．5次，患者手术依从性良好，观察病例无角膜穿孔，无睑球粘连。结膜囊狭窄5例，角膜斑翳5例，角膜血管化2例。结论采用自制全结膜囊羊膜固定器手术，缩短手术时间，无创伤，重症烧伤患者可多次重复手术，特别适合重症眼表烧伤早期治疗，减少晚期严重并发症的发生。

简介：AIM:Toadaptthelowvision-relatedqualityoflife(LVQOL)instrumentintoTurkishlanguageandtoassessitsvalidityandreliability.METHODS:Thestudywasconductedin387patientsattendingtheCentreofLowVisionRehabilitation,FacultyofMedicine,AnkaraUniversity.Forstatisticalanalyses,theSpearman’scorrelationcoefficient,Cronbach’salphacoefficientandConfirmatoryFactorAnalysis(CFA)wereused.RESULTS:AccordingtoresultsofCFA,theiteminthe'Adjustment'subscalebecauseofhavingthefactorloadingbelow0.40,wasexcludedfromthequestionnaire.ThereliabilityofthequestionnairewasassessedaccordingtoCronbach’salphacoefficients.Thereliabilityofthe'DistanceVision,Mobility,andLighting'subscalewas?琢=0.863;ofthe'Adjustment'subscalewas?琢=0.694;'ReadingandFineWork'was?琢=0.791,and'ActivitiesofDailyLiving'was?琢=0.770.Sotheseresultsindicatethatthequestionnaireisreliabletomeasurethevisionrelatedqualityoflifeoflow-visionpatients.Thecorrelationsbetweenthesubscaleswerealsoanalyzed,andthecorrelationbetween'Adjustment'and'ReadingandFineWork'wasfoundtobethelowest(rs=0.336,P<0.001),whereasthestrongestcorrelationwasfoundbetweenthe'ReadingandFineWork',and'ActivitiesofDailyLiving'.Additionally,the'Adjustment'dimensionshowedthestrongestcorrelationwithonly'DistanceVision,Mobility,andLighting'dimension.CONCLUSION:Afterremovingthelastitemintheseconddimension,theTurkishadaptationofalldimensionsoftheLVQOLhasbeenshowntobereliable,validandsuitableforuseinpatientswithlowvisioninTurkey.

简介：目的探讨表而麻醉下小切口囊袋内圈垫式切核白内障囊外摘除术的手术疗效。方法表面麻醉下对116眼（96例）白内障行小切口囊袋内圈垫式切核白内障摘除术,记录术中患者眼疼痛情况及手术时间,术后角膜水肿情况、最佳矫正视力及手术并发症。结果116眼手术均在表面麻醉下完成,术中疼痛分级情况：0级96眼,1级14眼,2级6眼,3级0眼。手术平均时间为13.6±3.5min。术后第1天最佳矫正视力情况：0.2-0.4者16眼,0.5-0.8者82眼,≥1.0者18眼。术后第一天角膜水肿情况：角膜内皮纹样水肿28眼,均于术后3天左右消退;局部斑片样混浊3眼,术后1周内消退。结论表面麻醉下小切口囊袋内圈垫式切核白内障摘除术具有术中操作简便,手术时间短,前房操作空间大,并发症少等优点。

简介：AIM:Toexploretheeffectofsaturatedhydrogensalineonbluelight-inducedretinaldamageinrats.·METHODS:Theretinaldamageofratswasinducedbybluelightexposurefor6hoursandexamined8hours,16hoursand24hoursaftertheexposure.OnehundredfemaleSprague-Dawleyratswererandomlydividedintofourgroups.Group1included30ratsreceivedlightexposurewithoutanyothertreatment.Group2included30ratsreceivedlightexposurewithintraperitonealinjectionofnormalsaline.Group3included30ratsreceivedlightexposurewithintraperitonealinjectionofsaturatedhydrogensaline.AndGroup4includedtheother10ratswhichdidnotreceiveanytreatment.Theamountofintraperitonealinjectionofsaturatedhydrogensalineandnormalsalinewascalculatedintheratioof1ml/100gofratweight.SpecimenswerecollectedandprocessedbyH-Estaining,ultrastructureobservation,biochemicalmeasurement.Morphologicalchangeswereobservedbylightmicroscopeandtransmissionelectronmicroscope(TEM)andtheretinalouternuclearlayer(ONL)thicknesswasmeasuredbyIPP6.0,whilethemalondialdehyde(MDA)wasmeasuredbycolorimetricdeterminationat532nm.·RESULTS:AlthoughthestructureofretinainGroup1andGroup2wasinjuredheavily,theinjuryinGroup3wasmild.ThedifferencesbetweenGroup1andGroup2werenotsignificant.ComparedwiththeratsinGroup1andGroup2,theonesinGroup3hadmoreclearlydemarcatedretinastructureandmoreorderedcellsbylightmicroscopeandTEMobservation.TheONLthicknesses(400times)offourgroupsateachtimepointexceptbetweenGroup1andGroup2weresignificantlydifferent(P<0.05).ThethicknessesoftheONLinGroup1atthreetimepointswere30.41±4.04μm,26.11±2.82μmand20.63±1.06μm,inGroup2were31.62±4.54μm,25.08±3.63μmand19.07±3.86μm,inGroup3were29.75±3.62μm,28.83±1.97μmand27.61±1.83μm.InGroup4themeanofthethicknesswas37.35±1.37μm.Astimewentby,thedamageg

简介：AIM:Anaerobicbacteriacancauseocularinfections.WetestedtheOxyPlateTMAnaerobicSystem(OXY)toisolatepertinentanaerobicbacteriathatcancauseoculardisease.METHODS:OXY,whichdoesnotrequiredirectanaerobicconditions(i.e.bags,jars),wascomparedtoconventionalisolationofincubatingculturemediainanaerobicbags.Standardcoloniescountswereperformedonanaerobicocularbacterialisolatesunderaerobicandanaerobicconditions(anaerobicbags)usingagarmedia:1)OXY(aerobiconly),2)5%sheepblood(SB),3)Chocolate,and4)Schaedler.Thebacteriatestedwerede-identifiedocularisolatesculturedfromendophthalmitisanddacryocystitisthatinclude10Propionibacteriumacnesand3Actinomycesspecies.Thecolonycountsforeachbacteriaisolate,oneachculturingcondition,wererankedfromlargesttosmallest,andnon-parametricallycomparedtodeterminethebestculturingcondition.RESULTS:Allanaerobicconditionswerepositiveforalloftheanaerobicisolates.SBandSchaedler’sagarunderaerobicconditionsdidnotsupportthegrowthofanaerobicbacteria.SparsegrowthwasnotedonchocolateagarwithPropionibacteriumacnes.Asananaerobicsystem,SBinananaerobicbagisolatedhighercolonycountsthanOXY(P=0.0028)andchocolateagar(P=0.0028).CONCLUSION:AlthoughOXYdidnottesttobemoreefficientthanotheranaerobicsystems,itappearstobeareasonablealternativeforisolatinganaerobicbacteriafromocularsites.Theuseofanagarmediuminaspeciallydesignedplate,withouttherequirementofananaerobicbag,renderedOXYasanadvantageoverotheranaerobicsystems.

简介：AIM:TodiscusstheimpactofLyciumBarbarumPolysaccharide(LBP)andDanshensupurifiedfromTraditionalChineseMedicine(TCM)onvascularendothelialgrowthfactor(VEGF)ofrabbitswithretinalneovascularization.METHODS:Fortyrabbitsweredividedintonormalcontrolgroup,modelcontrolgroup,LBPgroupandDanshensugroup.Animalsinthenormalcontrolgroupwerefedinthenormaloxygenenvironment.Animalsintheotherthreegroupswereputintotheenvironmentwith70%oxygenfor5daysinordertobuildthemodelofoxygen-inducedvascularproliferationretinopathy.AndthendifferentTCMextractwasinjectedintotheabdominalcavitiesoftheseannimals.After7days,theVEGFcontentofintheserumofrabbitwasmeasuredbydoubleantibodysandwichmethod.RESULTS:DataanalysisindicatedthatVEGFcontentwasasfollows:Danshensugroupwaslowerthanmodelcontrolgroup(12.92±3.84ng/Lvs19.32±4.15ng/L,P<0.05);LBPgroupandnormalcontrolgroupwerelowerthanmodelcontrolgroup(12.92±3.84ng/L,9.26±1.61ng/Lvs19.32±4.15ng/L,P<0.01);totalbloodviscosity,plasmaviscosity,cholesterolcontent,fibrinogencontentandtriacylglycerolcontentafterperitonealinjectionofLBPandDanshensuwereobviouslylowerthanbeforeinjection.CONCLUSION:TCMextract-LBPandDanshensucanprominentlyreducethecontentofVEGFintheprocessofvascularproliferativeretinopathyofrabbit;canpreventtheoccurrenceofretinalmicrovasculardiseasebyimprovingpartialoxygen-deficientenvironmentoraffectingallkindsofnewgrowthfactor.

简介：AIM:TopresenttheresultsofimplantationofIakymenkokeratoprosthesisinfivepatientswithvascularizedcornealleukomacausedbysevereocularinjury.·METHODS:Iakymenkokeratoprosthesiswasimplantedinto5eyesof5patients:4patientsweresufferedfromchemicalburnsand1patientfromexplosiveinjury.Thepreoperativevisualacuityrangedfromlightperceptiontohandmotion.Theimplantationsurgerywascomposedoftwo-stageprocedures.Thefollow-upperiodwasfrom9monthsto11years.Theoutcomemeasureswerevisualacuity,retention,andcomplicationsofthekeratoprosthesis.·RESULTS:Visionimprovementswereachievedinmostpatients.Allkeratoprosthesiswereretainedwithinthefollow-upperiod.Cornealmeltingoccurredinonepatientandfibrousclosureinanotherpatient,bothofwhichweresuccessfullytreated.Retinaldetachmentoccurredinonepatientaftersurgery.·CONCLUSION:Iakymenkokeratoprosthesisseemstobeapromisingalternativeforthepatientswithseverecornealinjury,butfurtherinvestigationisneededtoevaluatetheroleofIakymenkokeratoprosthesis.

简介：AIM:Toinvestigatethefrequencyofidiopathicphacodonesis(IP)insenilecataractsubjectsandtheshort-termclinicaloutcomesfollowingcataractsurgery.METHODS:Thisinstitutionalcase-controlstudyincluded1301consecutivelow-incomecataractsubjectsfromJunetoNovember2009.Anteriorsegmentwerecarefullyevaluatedwithdilatedpupilunderslit-lamp.IPwerescreenedandgradedbyacriteriasetbytheauthors.Riskfactors,surgicaloutcomes,andoperativecomplicationswereanalyzed.RESULTS:Atotalof42subjects(3.2%)withIPwerediagnosedandclassifiedasgrade1(36subjects),grade2(5subjects)andgrade3(1subject).HarderlensesandintumescentcataractswereobservedintheIPgroupthanthecontrolgroup(P<0.05).Logisticsregressiontestalsoindicatedthemainriskfactorwasthehardnessofthelens.Theincidenceofzonulardialysisduringsurgerywas23.8%(10eyes),whichwassignificantlyhigherthanthecontrols(0.7%,P<0.001).Visualoutcomesofthetwogroupswerenotstatisticallyorclinicallysignificant.CONCLUSION:HardnucleusandintumescentcataractarerelatedtoIPinsenilecataractsubjectsinQinghai,China.Withmorecarebeingtaken,grade1andsomeofthegrade2IPsubjectsachievedsimilarsurgicaloutcomesascomparedtocontrols.

简介：<正>DirSir,IamdoctorGuo-YuanYang,fromtheDepartmentofOphthalmologyofWestChinaHospitalofSichuanUniversityinChengdu,SichuanProvince,China.Iwritetopresentacasereportofposteriorlentiglobuswithcataract.

简介：AIM:Toevaluatechangesintheanteriorchamberdepth(ACD),crystallinelensthickness(LT)anditsrefractivepowerafterlaserinsitukeratomileusis(LASIK).·METHODS:Inallcases,thepreoperativeandpostoperativecentralACDwhichweremeasuredwithPentacam,Orbscan,IOL-MasterandA-scanultrasonography,centralcornealtruenetpowerwhichwasmeasuredwiththePentacam,OrbscanandIOL-Master,axiallength(AL)whichwasmeasuredwithIOL-MasterandLTwhichwasmeasuredwiththeA-scanultrasonographywerecomparedusingthepairedsamplettest.OcularrefractiveerrorsandlensrefractivepoweratcornealplanewerecalculatedandtheircorrelationswerealsoevaluatedbeforeandafterLASIK.RESULTS:At1weekafterLASIK,LTandcrystallinelensrefractivepoweratcornealplane(Dlens)whichwereassociatedwiththeIOL-MasterandPentacamincreasedsignificantly(P≤0.005),ACDdecreasedsignificantly(P≤0.001),butnosignificantincreasewasobservedintheDlenswhichwasassociatedwiththeOrbscan(P=0.261).SignificantcorrelationsbetweenthechangesintheocularrefractiveerrorsandDlenswhichwereassociatedwiththePentacamwereobservedat1weekand6monthsafterLASIK(P=0.028;P=0.001).CONCLUSION:LTincreasedsignificantlyafterLASIK,andthismightpartiallyleadtoACDdecrease,Dlensincreaseandasmallquantityofmyopicregression.

简介：AIM:ToexploretheinhibitoryeffectofasustainedcyclosporinA(CsA)deliverymicrosphere(CsA-MS)onposteriorcapsularopacification(PCO)inrabbiteyesaftercataractextraction.·METHODS:TwentyNewZealandwhiterabbitsacceptedcataractextractionplusintraocularlensimplantationandtheirlefteyeswereintraoperativelyinjectedCsA-MSpreparedusingpolymerpolylactioglycolicacid(PLGA)asacarrierandtheirrighteyeswereinjectedwithemptyMS.Thechangesincornea,anteriorchamberreaction,intraocularpressure,PCOandCsAconcentrationinaqueoushumorwereexaminedpostoperativelyandalltheeyeswereenucleated3monthsaftersurgeryforhistopathologicalandmorphologicalexaminationwithlightmicroscopyandelectronmicroscopy.·RESULTS:Conjunctivalhyperemia,cornealedema,intraocularpressureandanteriorchamberresponseofexperimentalandcontroleyesweresimilar,whilePCOinCsAMSinjectedeyeswasgreatlyimprovedcomparedwiththatincontroleyes.PosteriorcapsulesinCsA-MSinjectedeyesweresmoothandlensepithelialcells(LEC)didnotproliferatesignificantly(P>0.05),whileLECinposteriorcapsuleofcontroleyeshaddifferentdegreesofproliferationandcorticalregeneration.LECinCsA-MSinjectedeyeswerenotfunctionallyactiveandunderwentapoptosis,whereasLECincontroleyeswerefunctionallyactive(F-test,P=0.025).Inaddition,thecornealultrastructureshowednodifferencesbetweenCsA-MSandMSinjectedeyes.CONCLUSION:CsA-MShashighbioavailabilityinrabbiteyesandcouldinhibitpostoperativePCOoccurrenceanddevelopmentduringthestudyperiod,suggestingthatCsA-MSmaybeapromising,effectiveandsafeadministrationroutetopreventPCOinclinic.

简介：AIM:Toinvestigatetheefficacyofnon-buckledvitrectomywithclassicalendotamponadeagentsinthetreatmentofprimaryretinaldetachment(RD)complicatedbyinferiorbreaksandproliferativevitreoretinophathy(PVR).METHODS:Aretrospective,consecutiveandcaseseriesstudyof40patientswithinferiorbreakRDandPVR≥C1wasconducted.Allpatientsunderwentastandard3-port20-gaugeparsplanavitrectomy(PPV)withgasorsiliconeoiltamponadewithoutsupplementaryscleralbuckling.Thevitreousandallproliferativemembranewerecompletelyremoved,andretinectomywasperformedwhennecessary.Themeanfollow-upwas12.5months.Theprimaryandfinalanatomicsuccessrate,visualacuityandcomplicationswererecordedandanalyzed.RESULTS:Primaryanatomicsuccessratewasachievedin35of40eyes(87.5%)andthefinalanatomicsuccessratewas100%.ThemostcommoncauseofredetachmentwasrecurrentPVR.Thebest-correctedvisualacuity(BCVA)atfinalfollow-upwasimprovedin34eyes(85%),remainedstablein1eye(2.5%),andworsenedin5eyes(12.5%).Themeanvisualacuityatfinalfollow-upwasimprovedsignificantly(P=0.000).CONCLUSION:ThisretrospectivestudyprovidesevidencethatvitrectomywithoutscleralbucklingseemedtobeaneffectivetreatmentforinferiorbreakRDwithPVR.Withcompleteremovalofvitreousandproliferativemembranesandtimingofretinectomy,theinferiorbreakswhichcomplicatedwithPVRcouldbeclosedsuccessfullywithoutadditionalscleralbuckling.

简介：AIM:ToinvestigatetheeffectofY-27632onthesurvivalandneuriteoutgrowthoftheculturedretinalneurocytes.METHODS:Afterthepostnatalday2-3,Sprague-Dawleyretinalneurocyteswereculturedfor48hours,theculturemediawasreplacedwithserum-freemedia(controlgroup)andserum-freemediacontained30μmol/LY-27632(Y-27632group),andthecellswerecontinuallyculturedanother48hours.Theculturedretinalneurocyteswereidentifiedwithanti-neuronspecificenolase(NSE)immunocytochemistry.ThesurvivalstateofthosecellswasestimatedbyMTTassay,andtheneuriteoutgrowthofthosecellswasevaluatedbythecomputerizedimage-analysissystem.RESULTS:Comparedwiththecontrolgroup,theabsorbancevaluesofcellssurvivalinY-27632groupincreased12.90%and33.33%respectivelyafter72and96hoursculture.Y-27632hadnosignificanteffectonthediameterofculturedretinalneurocytes.Comparedwiththecontrolgroup,Y-27632inducedastableimprovementofneuriteoutgrowthofretinalneurocytesafter72and96hoursculture(P=0.001).CONCLUSION:Y-27632couldpromotethesurvivalandneuriteoutgrowthoftheearlypostnatalculturedretinalneurocytes.