简介：作者对23例已确诊的小肠出血的定位，定性诊断进行回顾分析，结果显示，肿瘤、血管畸形是小肠出血的前3位病因，分虽占39.13%,21.74%,17.39%；选择性动脉造影对肿瘤有较大的价值，核素扫描适应小肠憩室出血，推进式小肠镜适应空肠上部病变；对剖腹探查不能发现病灶的病例，术中内镜会有所收获。

简介：目的了解B超在诊断肝脓肿中的作用。方法回顾分析我院自1998年-2003年23例肝脓肿的诊治经过，并经手术及穿刺证实。结果超声诊断为肝脓肿的患者20例．其中12例经过动态跟踪观察确诊。误诊3例。结论腹部B超对诊断肝脓肿具有重要的临床指导意义。

简介：AIMTocharacterizepunctualmutationsin23SrRNAgeneofclarithromycin-resistantHelicobacterpylori(H.pylori)anddeterminetheirassociationwiththerapeuticfailure.METHODSPCRproductsof23SrRNAgeneVdomainof74H.pyloriisolates;34resistanttoclarithromycin(29fromalow-riskgastriccancer(GC)population:Tumaco-Colombia,and5fromahigh-riskpopulation:Tuquerres-Colombia)and40fromasusceptiblepopulation(28fromTumacoand12fromTúquerres)weresequencedusingcapillaryelectrophoresis.TheconcordancebetweenmutationsofVdomain23SrRNAgeneofH.pyloriandtherapeuticfailurewasdeterminedusingtheKappacoefficientandMcNemar’stestwasperformedtodeterminetherelationshipbetweenH.pylorimutationsandclarithromycinresistance.RESULTS23SrRNAgenefromH.pyloriwasamplifiedin56/74isolates,ofwhich25wereresistanttoclarithromycin(20fromTumacoand5fromTúquerres,respectively).In17resistantisolates(13fromTumacoand4fromTúquerres)thefollowingmutationswerefound:A1593T1,A1653G2,C1770T,C1954T1,andG1827CinisolatesfromTumaco,andA2144GfromTúquerres.ThemutationsT2183C,A2144GandC2196TinH.pyloriisolatesresistanttoclarithromycinfromColombiaarereportedforthefirsttime.NoassociationbetweentheH.pylorimutationsandinvitroclarithromycinresistancewasfound.However,therapeuticfailureoferadicationtreatmentwasassociatedwithmutationsof23SrRNAgeneinclarithromycin-resistantH.pylori(κ=0.71).CONCLUSIONThetherapeuticfailureoferadicationtreatmentinthetwopopulationsfromColombiawasassociatedwithmutationsofthe23SrRNAgeneinclarithromycinresistantH.pylori.

简介：胆总管结石、胆总管梗阻是临床常见的疾病．它可以引起右上腹痛、黄疸、畏寒发热等胆道感染的症状，其治疗方法既往是以手术治疗为主、自从开展经内镜逆行胰胆管造影(ERCP)后为胆道疾病的诊断提供了新的有效的方法。内镜下十二指肠乳头括约肌切开术（EST)是由ERCP的临床应用中发展起来的一项治疗胆道疾病，乳头肌狭窄的安全有效的新技术．我院近一年来开展了EST治疗胆总管梗阻，胆管结石，乳头狭窄的病人共23例．现报告如下：