简介:AIM:ToinvestigatetheefficacyofFerrararings(FR)implantationinthetreatmentofkeratoconus.METHODS:Itwasaretrospectivecaseseriesdescriptivestudy.Thesamplewascomprisedof50patients79eyesdiagnosedwithprogressivekeratoconus.Thisincluded24(48%)malesand26(52%)femalesbetweentheageof13and44years.AllparticipantsunderwentsurgicalimplantationofFRintheperiodbetweenJanuary2009andSeptember2010atJordanUniversityHospital.Thoroughophthalmologicexaminationswereappliedtomeasurevitalvariablesforeachpathologicalconditionbeforeandaftersurgery.RESULTS:Findingsindicatedanoverallsignificantpostoperativeimprovementinbothuncorrectedvisualacuity(UCVA)andbestspectaclecorrectedvisualacuity(BSCVA)throughoutfollowupvisits.Moreover,resultsillustratedasignificantdecreaseinsphericalequivalent(SE)andkeratometricreadings(lower,higherandtheaverage).CONCLUSION:Surgicalinterventionstrategiesarebeingfrequentlydevelopedtomeettheneedsofpatientswithkeratoconus.TheimplantationofFerrararingshasproventobeasafeandfeasiblealternativeprocedureforthetreatmentofmild-moderatekeratoconusespeciallyforpatientswithcontactlensesintolerance.Wehavefoundthatthisprocedurehasimprovedvisualoutcomesinalleyesstudied.Nevertheless,furtherresearchisneededtoinvestigatelongtermoutcomes.
简介:AIM:Toevaluatetheefficacy,safetyandstabilityofposteriorchamberphakicintraocularlensimplantationforthecorrectionofhighmyopia.METHODS:Retrospectivecasereviewof82eyes(43patients)undergoingimplantableColiamerlens(ICL)placementbyasinglesurgeon(Xiao-WeiGao)tocorrectpreoperativemeansphericalequivalentsbetween-9.00diopter(D)and-23.00D.Mainoutcomemeasuresincludeduncorrectedvisualacuity(UCVA),refraction,bestspectacle-correctedvisualacuity(BSCVA),endothelialcelldensity(ECD),intraocularpressure(IOP),lenstransparency,postoperativeuveitis.Visanteanteriorsegmentopticalcoherencetomography(AS-OCT)wasusedtomeasureanteriorchamberdepth(ACD)andthepositionofICL.RESULTS:Meanfollow-upwas6.54±3.26months(range3-12months).Predictabilityofthemanifestsphericalequivalent(SE)refractiontowithin±1.OODwasachievedin88%ofeyesand±0.50Din72.5%ofeyes.ThemeanpostoperativemanifestSErefractionwas-1.85±0.72D,with96.34%ofeyesmaintainingorgaining≥1line(s)ofBSCVA.Themean3-monthpostoperativeECDdecreasedbuthadnostatisticallydifferencecomparedwiththepreoperativeECD.Ofthe7eyes(8.54%)withamildtransientincreaseinintraocularpressure(upto30mmHg),nonerequiredasecondsurgicalprocedureorprolongedtopicalmedication.Therewasnolossoflenstransparency.Pigmentedprecipitateswereobservedin5eyes(6.09%).ThemeanpreoperativeACDmeasuredwithAS-OCTwas3.28±0.14mm,threemonthsaftersurgery,themeanACDwas2.45±0.22mm.Anteriorchamberdepthshowedastatisticallysignificantreduction.Oneeye(1.22%)hadICLspontaneousrotation,81eyes(98.78%)ofthelensremainedcorrectlycentered.CONCLUSION:TheimplantationofICLisaneffectivesurgicaloptionforthemanagementofhighmyopia.Butitslongtimeeffectandsafetystillneedmoretimetoprove.
简介:AIM:Toevaluatetheefficacyofintralesionalradiofrequencyablationinthetreatmentofperiorbitalsyringomas.·METHODS:Wetriedtheintralesionalradiofrequencyablationfor64patientswithperiorbitalsyringomasfrom2007to2011.Theoperationwasperformedunder2.5loupemagnifications.Thehandpiecewasassembledwithaneedleelectrodeandconnectedtotheradiofrequencyablationapparatus.Theelectrodewastheninsertedintothetargetlesionsindermisanddeliveringinjurytothebaseofthesetumors.Resultswereassessedclinicallybycomparingpre-andpost-treatmentphotographsandpatientsatisfactionrates.·RESULTS:Clinicalimprovementincreasedwitheachsubsequenttreatmentsession.Thepercentofpatientswhoseclinicimprovementgradewere≥3aftereachsessionwasrespectively71.9%(Session1),83.3%(Session2),and100%(Session3).Thestatisticalresultsindicatedtheconcordanceoftheclinicalassessmentandthesatisfactionlevelofpatients(kappa=0.78ofthesession1;kappa=0.82ofthesession2).Themajorityofpatientshadgoodorexcellentcosmeticresults.Postoperatively,therewerenopermanentsideeffectsorrecurrences.·CONCLUSION:Asanewtechniqueofminimallyinvasion,theintralesionalradiofrequencyablationwasfoundtobeaneffective,inexpensive,highlypreciseandsafewayoftreatingperiorbitalsyringomas.
简介:AIM:Toreporttheeffectivenessandsafetyofprimary23-Gauge(G)vitreoretinalsurgeryforrhegmatogenousretinaldetachment(RRD).·METHODS:Inthisretrospectivestudy,49eyesof49consecutivepatientswhounderwentprimary23-Gtransconjunctivalsuturelessvitrectomy(TSV)forRRDbetweenJanuary2007andJuly2009atourinstitutionwereevaluated.·RESULTS:Meanfollow-uptimewas8.9±7.7months(1-28months).Retinalreattachmentwasachievedwithasingleoperationin47(95.9%)of49eyes.Intwoeyes(4.1%),retinalredetachmentduetonewbreakswassuccessfullytreatedwithreoperationusingthe23-GTSVsystem.MeanlogMARvisualacuitywas2.01±0.47preoperativelyand1.3±0.5postoperatively(P<0.001,Pairedt-test).Meanpreoperativeintraocularpressure(IOP)was14.1±2.8mmHg.MeanpostoperativeIOPwas12.3±3.6mmHgat1day,13.1±2.1mmHgat1week,14.3±2.2mmHgat1month.Iatrogenicperipheralretinalbreakwasobservedin1eye(2.0%)intraoperatively.Nosutureswererequiredtoclosethescleralorconjunctivalopenings,andnoeyesrequiredconvertionofsurgeryto20-Gvitrectomy.·CONCLUSION:Primary23-GTSVsystemwasobservedtobeeffectiveandsafeinthetreatmentofRRD.
简介:AIM:TotrainTibetanmonkey(Macacathibetana)forintraocularpressure(IOP)measurementinconsciousstateandobtainnormalIOPinconsciousTibetanMacaque.·METHODS:Thetrainingwasbasedonaward-conditionedbehavior.Foodstimulationandhuman-animalinteractionwereusedinthistraining.·RESULTS:TrainedTibetanmonkeyscalmlyacceptedIOPmeasurementbytheTonoVet?誖reboundtonometerwithoutsedationoranesthesiaandtheirIOPvaluesweresimilartootherprimates.·CONCLUSION:Human-cultivatedThibetanmonkeysaretamable,andcanbeusedforbiomedicalresearchsuchasophthalmicresearchwithoutanesthesia.
简介:AIM:ToexploretheinhibitoryeffectofasustainedcyclosporinA(CsA)deliverymicrosphere(CsA-MS)onposteriorcapsularopacification(PCO)inrabbiteyesaftercataractextraction.·METHODS:TwentyNewZealandwhiterabbitsacceptedcataractextractionplusintraocularlensimplantationandtheirlefteyeswereintraoperativelyinjectedCsA-MSpreparedusingpolymerpolylactioglycolicacid(PLGA)asacarrierandtheirrighteyeswereinjectedwithemptyMS.Thechangesincornea,anteriorchamberreaction,intraocularpressure,PCOandCsAconcentrationinaqueoushumorwereexaminedpostoperativelyandalltheeyeswereenucleated3monthsaftersurgeryforhistopathologicalandmorphologicalexaminationwithlightmicroscopyandelectronmicroscopy.·RESULTS:Conjunctivalhyperemia,cornealedema,intraocularpressureandanteriorchamberresponseofexperimentalandcontroleyesweresimilar,whilePCOinCsAMSinjectedeyeswasgreatlyimprovedcomparedwiththatincontroleyes.PosteriorcapsulesinCsA-MSinjectedeyesweresmoothandlensepithelialcells(LEC)didnotproliferatesignificantly(P>0.05),whileLECinposteriorcapsuleofcontroleyeshaddifferentdegreesofproliferationandcorticalregeneration.LECinCsA-MSinjectedeyeswerenotfunctionallyactiveandunderwentapoptosis,whereasLECincontroleyeswerefunctionallyactive(F-test,P=0.025).Inaddition,thecornealultrastructureshowednodifferencesbetweenCsA-MSandMSinjectedeyes.CONCLUSION:CsA-MShashighbioavailabilityinrabbiteyesandcouldinhibitpostoperativePCOoccurrenceanddevelopmentduringthestudyperiod,suggestingthatCsA-MSmaybeapromising,effectiveandsafeadministrationroutetopreventPCOinclinic.
简介:AIM:Toinvestigatetheefficacyofnon-buckledvitrectomywithclassicalendotamponadeagentsinthetreatmentofprimaryretinaldetachment(RD)complicatedbyinferiorbreaksandproliferativevitreoretinophathy(PVR).METHODS:Aretrospective,consecutiveandcaseseriesstudyof40patientswithinferiorbreakRDandPVR≥C1wasconducted.Allpatientsunderwentastandard3-port20-gaugeparsplanavitrectomy(PPV)withgasorsiliconeoiltamponadewithoutsupplementaryscleralbuckling.Thevitreousandallproliferativemembranewerecompletelyremoved,andretinectomywasperformedwhennecessary.Themeanfollow-upwas12.5months.Theprimaryandfinalanatomicsuccessrate,visualacuityandcomplicationswererecordedandanalyzed.RESULTS:Primaryanatomicsuccessratewasachievedin35of40eyes(87.5%)andthefinalanatomicsuccessratewas100%.ThemostcommoncauseofredetachmentwasrecurrentPVR.Thebest-correctedvisualacuity(BCVA)atfinalfollow-upwasimprovedin34eyes(85%),remainedstablein1eye(2.5%),andworsenedin5eyes(12.5%).Themeanvisualacuityatfinalfollow-upwasimprovedsignificantly(P=0.000).CONCLUSION:ThisretrospectivestudyprovidesevidencethatvitrectomywithoutscleralbucklingseemedtobeaneffectivetreatmentforinferiorbreakRDwithPVR.Withcompleteremovalofvitreousandproliferativemembranesandtimingofretinectomy,theinferiorbreakswhichcomplicatedwithPVRcouldbeclosedsuccessfullywithoutadditionalscleralbuckling.
简介:今天,我们在这里召开2005年全国防盲工作研讨会。这次会议的主要内容是:分析全国防盲工作面临的形势和挑战,研究开展防盲工作的重点和策略;研究制定2006-2010年全国防盲工作规划。同时,还要对“视觉第一中国行动”二期启动以来的工作进行总结,对中期评估事宜和下一步工作进行部署。两天的时间,任务还是比较重的,我希望大家借此机会,广泛交流各地防盲治盲工作情况,借鉴各地有益的工作经验,在充分研讨,制定出我国2006-2010年防盲工作规划的同时,研究探索适合我国国情、进一步推进我国防盲治盲工作的政策措施、有效途径。
简介:AIM:Toreportthelong-termvision-threateningcomplicationsinpatientswhounderwentphakicintraocularlens(pIOLs)implantationforhighmyopia.METHODS:Thisstudywasdesignedfromaconsecutiveseriesofphakicintraocularlenscomplicationandcorrectivesurgeries.Sixteeneyesof13patientshadimplantationofphakicintraocularlensforcorrectionhighmyopiaanddevelopedseriouscomplicationshavebeenincludedinthisstudy.Themeanageofpatientswas38.6±6.35y(range32-50y)andthemeantimeofhistoryofpIOLimplantationforhighmyopiawas6±2y(range2-10y).Beforecorrectivesurgery,bestspectaclecorrectivevisualacuity(BSCVA)rangedfromperceptionto20/200intheeyesinwhichseverecomplicationsoccurred.RESULTS:Cornealdecompensationoccurredin12eyesof9highmyopicpatientsafteranteriorchamberpIOLimplantation.Rhegmatogenousretinaldetachment(RRD)occurredin4eyesof4highmyopicpatientsfollowinganteriorchamberandposteriorchamberpIOLimplantation.Patientswithcornealdecompensation,hadcombinedproceduresconsistingofpIOLremovalandpenetratingkeratoplasty(PKP).RemovalsofpIOL,phacoemulsificationandparsplanavitrectomy(PPV)withsiliconeoiltamponadewereperformedinpatientswithRRD.Aftercorrectivesurgeries,allpatientsbutone(P+,patient2,righteye)achievedmoderateBSCVArangedfrom20/200to20/50atthelastvisit.CONCLUSION:PhakicIOLsmaybeeffectiveforthecorrectionofhighmyopia.AlthoughtheseIOLsmayhaveseverecomplicationsanditaffectssafetyandefficacyofthissurgery.Asseenhere,cornealdecompensationandrhegmatogenousretinaldetachmentarepossiblepostoperativevision-threateningcomplicationsofphakicIOLs.Patientsmustbecarefullyexaminedbeforeandaftersurgeryforpossibleendothelialcelllossandvitreoretinalproblems.
简介:AIM:Anaerobicbacteriacancauseocularinfections.WetestedtheOxyPlateTMAnaerobicSystem(OXY)toisolatepertinentanaerobicbacteriathatcancauseoculardisease.METHODS:OXY,whichdoesnotrequiredirectanaerobicconditions(i.e.bags,jars),wascomparedtoconventionalisolationofincubatingculturemediainanaerobicbags.Standardcoloniescountswereperformedonanaerobicocularbacterialisolatesunderaerobicandanaerobicconditions(anaerobicbags)usingagarmedia:1)OXY(aerobiconly),2)5%sheepblood(SB),3)Chocolate,and4)Schaedler.Thebacteriatestedwerede-identifiedocularisolatesculturedfromendophthalmitisanddacryocystitisthatinclude10Propionibacteriumacnesand3Actinomycesspecies.Thecolonycountsforeachbacteriaisolate,oneachculturingcondition,wererankedfromlargesttosmallest,andnon-parametricallycomparedtodeterminethebestculturingcondition.RESULTS:Allanaerobicconditionswerepositiveforalloftheanaerobicisolates.SBandSchaedler’sagarunderaerobicconditionsdidnotsupportthegrowthofanaerobicbacteria.SparsegrowthwasnotedonchocolateagarwithPropionibacteriumacnes.Asananaerobicsystem,SBinananaerobicbagisolatedhighercolonycountsthanOXY(P=0.0028)andchocolateagar(P=0.0028).CONCLUSION:AlthoughOXYdidnottesttobemoreefficientthanotheranaerobicsystems,itappearstobeareasonablealternativeforisolatinganaerobicbacteriafromocularsites.Theuseofanagarmediuminaspeciallydesignedplate,withouttherequirementofananaerobicbag,renderedOXYasanadvantageoverotheranaerobicsystems.